Normal anion gap metabolic acidosis can occur in

Questions 28

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Pediatric Musculoskeletal Disorders Questions

Question 1 of 5

Normal anion gap metabolic acidosis can occur in

Correct Answer: C

Rationale: Severe anemia can cause normal anion gap acidosis due to reduced oxygen delivery; others typically increase the anion gap.

Question 2 of 5

Duchenne muscular dystrophy (DMD) is the most common hereditary neuromuscular disease affecting all races and ethnic groups. All the following are features of DMD EXCEPT

Correct Answer: C

Rationale: Fasciculation is not a feature of DMD, which is characterized by progressive muscle weakness, scoliosis, contractures, cardiomyopathy, and intellectual impairment. Fasciculations are more typical of neurogenic conditions like ALS.

Question 3 of 5

In periodic paralysis, all the following are precipitating factors EXCEPT

Correct Answer: A

Rationale: A heavy fat meal is not a recognized trigger for periodic paralysis; the others (e.g., licorice via hypokalemia) can precipitate attacks.

Question 4 of 5

Guillain Barré syndrome is an autoimmune disorder often considered a postinfectious polyneuropathy involving mainly motor but also sensory and sometimes autonomic nerves. All the following are required in diagnosis EXCEPT

Correct Answer: B

Rationale: Muscle biopsy is not required for GBS diagnosis; CSF (elevated protein), EMG, and nerve studies are more relevant.

Question 5 of 5

Myasthenia gravis should be differentiated from other causes of neuromuscular blockade as organophosphate chemicals, botulism, and tick paralysis. Of the following, the MOST specific diagnostic test is

Correct Answer: C

Rationale: Anti-acetylcholine receptor (AChR) antibodies are the most specific diagnostic test for myasthenia gravis, present in 85-90% of cases.

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