Neoadjuvant chemotherapy treatment for cancer is given to facilitate surgical resection. When the outcomes of cancer therapies are evaluated, the terms complete response and partial response often are used. Partial response means that

Correct Answer: D

Rationale: The correct answer is D because in the context of neoadjuvant chemotherapy, a partial response means converting an unresectable tumor to a resectable one. This is crucial as it allows for successful surgical removal of the tumor. Choices A, B, and C do not accurately define partial response in the context of cancer therapy. A, stating 50% of patients demonstrating remission, is not specific to the change in resectability. B, mentioning 50% survival at 5 years, is more related to overall survival rather than the response to treatment. C, stating a reduction in tumor mass by >50%, does not necessarily imply a change in resectability status. Therefore, option D is the most appropriate definition of partial response in the given scenario.

Correct Answer: B

Rationale: The correct answer is B: Turtle sign. This occurs when the fetal head retracts against the perineum during delivery, resembling a turtle retracting into its shell. This indicates fetal shoulder dystocia, a serious complication. Gaskin sign (A) refers to the position of the mother during labor. Klumpke sign (C) is related to brachial plexus injuries during delivery. Chignon sign (D) is not a recognized term in obstetrics.

Correct Answer: C

Rationale: The correct answer is C: Premature rupture of membranes. Oligohydramnios is a condition characterized by low levels of amniotic fluid which can be caused by the premature rupture of membranes, leading to the leakage of amniotic fluid. This condition can result in various complications such as fetal growth restriction and compression of the umbilical cord. Maternal hypertension (choice A) is not a direct cause of oligohydramnios. Multiple gestations (choice B) may lead to polyhydramnios (excessive amniotic fluid) rather than oligohydramnios. Fetal macrosomia (choice D) is associated with increased amniotic fluid levels rather than decreased levels seen in oligohydramnios.

Correct Answer: C

Rationale: The correct answer is C: Hyperemesis gravidarum. This condition is characterized by severe nausea, vomiting, weight loss, dehydration in pregnancy. It is more severe than typical morning sickness (choice A) and is not specific to multiple gestation (choice B). Hypertensive disorders (choice D) typically present with high blood pressure, proteinuria, and edema, not just nausea and vomiting. Hyperemesis gravidarum requires medical intervention due to potential complications from dehydration and malnutrition.

Correct Answer: B

Rationale: Step 1: Feminizing adrenal tumors are not always carcinomas, so A is incorrect. Step 2: Virilizing tumors in women can originate from adrenal or extra-adrenal sites, so C is incorrect. Step 3: Virilizing adrenal tumors are usually benign, especially in children, so D is incorrect. Step 4: B is correct as feminizing adrenal tumors are rare but are the most common type of adrenal tumor causing gender symptoms.

Correct Answer: D

Rationale: Placental parasitation is associated with Malaria prenatally because the Plasmodium parasite can infect the placenta through the bloodstream, leading to severe complications for both the mother and the fetus. This infection can result in low birth weight, preterm birth, and even stillbirth. Candidiasis, Tuberculosis, and Multiple gestation are not directly associated with placental parasitation. Candidiasis is a fungal infection, Tuberculosis is a bacterial infection, and Multiple gestation refers to carrying more than one fetus during pregnancy. Therefore, the correct answer is D, Malaria prenatally, due to the direct impact of Plasmodium parasite on the placenta and its implications on pregnancy outcomes.

Correct Answer: A

Rationale: The correct answer is A: Immune globulin. Post bone marrow transplant, immune globulin is used to decrease the risk of graft-versus-host reaction by providing passive immunity. This helps in reducing the chances of the donor's immune cells attacking the recipient's tissues. Immune globulin does not suppress the immune system like cyclosporine (B) or systemic corticosteroids (D) do, which could increase the risk of infections post-transplant. Prophylactic antibiotics (C) are used to prevent infections but do not specifically target graft-versus-host reaction.

Correct Answer: D

Rationale: The correct answer is D because hypoplastic left heart syndrome involves underdevelopment of the left ventricle, aortic valve, and aortic arch. The left ventricle is typically small and unable to adequately pump blood to the body. The aortic valve is often malformed, leading to difficulties in blood flow from the heart to the body. Additionally, the aortic arch may be narrow or underdeveloped, further impacting blood circulation. Choice A is incorrect as it includes the pulmonary veins, which are not typically affected in hypoplastic left heart syndrome. Choice B is incorrect as it focuses on the left atrium and pulmonary vessels, which are not the primary structures affected in this condition. Choice C is incorrect as it mentions the aorta arch, venacava, and right atrium, which are not primarily associated with hypoplastic left heart syndrome.

Correct Answer: D

Rationale: Step-by-step rationale: 1. External examination can reveal the position of the baby's head. 2. Ultrasound can confirm the baby's position accurately. 3. Physical exam and pelvic exam findings can provide additional information. 4. Combining both methods (A and B) ensures a comprehensive assessment for accurate diagnosis. Summary: - Choice A alone may not provide sufficient information. - Choice B alone may not be as accurate as combined with ultrasound. - Choice C is not specific to diagnosing occipito-posterior position. - Choice D is correct as it combines external examination, ultrasound, and physical exam for accurate diagnosis.