Neo-adjuvant chemotherapy means

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Pediatric Infectious Diseases Questions

Question 1 of 5

Neo-adjuvant chemotherapy means

Correct Answer: C

Rationale: Neo-adjuvant chemotherapy is given before surgery to shrink the tumor while it remains in place.

Question 2 of 5

The commonest translocation in infantile acute lymphoblastic leukemia is

Correct Answer: C

Rationale: t(4;11) (MLL rearrangement) is the most frequent translocation in infantile ALL, linked to poor prognosis.

Question 3 of 5

A boy with acute lymphoblastic leukemia is assigned to be of very high risk group if he had got which of the following features?

Correct Answer: D

Rationale: t(9;22) (Philadelphia chromosome) confers a very high risk in ALL due to poor prognosis.

Question 4 of 5

The LEAST likely presenting feature for a newly diagnosed 3-year-old girl with non-Hodgkin's lymphoma is

Correct Answer: D

Rationale: Jaundice is uncommon in non-Hodgkin lymphoma unless there is significant liver or biliary involvement.

Question 5 of 5

During follow up of a surgically resected brain tumor, the examination of choice to distinguish recurrent tumor from radiation necrosis is

Correct Answer: B

Rationale: Magnetic resonance spectroscopy differentiates tumor recurrence from radiation necrosis by metabolic profiling.

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