ATI RN
ATI RN Pharmacology Proctored Exam 2023 Questions
Question 1 of 5
Nefopam:
Correct Answer: B
Rationale: Nefopam is contraindicated in epilepsy due to its potential for lowering the seizure threshold.
Question 2 of 5
It is rational and advised therapeutic practice to commence treatment with the following drug using a loading dose if a rapid onset of action is required:
Correct Answer: C
Rationale: A loading dose achieves therapeutic levels quickly for drugs with long half-lives or urgent needs. Clozapine's slow titration avoids agranulocytosis, not rapid loading. Zolmitriptan, for acute migraine, acts fast without loading due to short half-life. Amiodarone, with a half-life of weeks, uses loading doses (e.g., 800-1600 mg/day) to rapidly control arrhythmias, rational for urgent onset. Levodopa's short half-life and titration in Parkinson's don't require loading. Doxazosin, for hypertension, starts low to avoid first-dose hypotension. Amiodarone's pharmacokinetics and arrhythmia urgency make loading advised, balancing efficacy and toxicity risks.
Question 3 of 5
The nurse is reviewing new medication orders that have been written for a newly admitted patient. The nurse will need to clarify which orders? Select all that apply.
Correct Answer: D
Rationale: Medication orders must be clear, complete, and appropriate for the patient's condition. Orders that include 'as needed' (PRN) medications, such as 'Docusate (Colace) as needed for constipation,' require clarification because they lack specific dosing instructions. The nurse must confirm the frequency, dosage, and indications for PRN medications to ensure safe administration. The other orders (Metformin, Sitagliptin, Simvastatin, and Irbesartan) are complete and do not require clarification. Therefore, the nurse should focus on clarifying the PRN order to avoid errors in medication administration.
Question 4 of 5
A patient being seen for skin concerns asks, 'What do keratolytic drugs remove?' What is the nurse’s best response?
Correct Answer: B
Rationale: Keratolytic drugs, such as salicylic acid, work by softening and removing the horny layer of the epidermis, which consists of dead skin cells. This helps treat conditions like psoriasis, warts, and calluses. They do not target the dermis (A), erythematous lesions (C), or hair follicles (D).
Question 5 of 5
Regarding diazepam:
Correct Answer: B
Rationale: Diazepam, a benzodiazepine, has active metabolites (e.g., desmethyldiazepam) with longer half-lives, contributing to its effects, so that's false. Activated charcoal is effective in overdose by adsorbing diazepam, reducing absorption, a true statement and standard intervention. It undergoes minimal, not extensive, enterohepatic recirculation, making that false. It's a GABA agonist, enhancing chloride influx via benzodiazepine receptors, not an antagonist, so that's incorrect. It also inhibits spinal reflexes, aiding muscle relaxation. The overdose utility of charcoal highlights its role in emergency management, binding unabsorbed drug in the gut, a key pharmacokinetic intervention distinct from flumazenil reversal.