Natural killer cells

Questions 60

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Pediatric Immunization Test Questions Questions

Question 1 of 5

Natural killer cells

Correct Answer: B

Rationale: NK cells lyse virally infected cells and tumor cells as part of innate immunity, without antigen presentation.

Question 2 of 5

The genes encoding which of the following can undergo hypermutation to create receptors that are an even better fit for foreign antigens?

Correct Answer: A

Rationale: BCRs undergo somatic hypermutation in B cells to enhance antigen affinity, unlike TCRs or MHCs.

Question 3 of 5

Which of the following is NOT true regarding effective immunogens?

Correct Answer: D

Rationale: Effective immunogens (e.g., proteins) don't require carriers; this is true for haptens, not standalone immunogens.

Question 4 of 5

Binds antigen

Correct Answer: C

Rationale: The Fab region binds antigens via its variable domains, formed by light and heavy chains.

Question 5 of 5

Pepsin cleaves what region of immunoglobulin?

Correct Answer: C

Rationale: Pepsin cleaves below the hinge region, producing F(ab')2 fragments.

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