ATI RN
NCLEX questions on chemotherapy drugs Questions
Question 1 of 5
Nalidixic acid is primarily active against
Correct Answer: D
Rationale: Nalidixic acid is primarily active against gram-negative bacteria, especially in the urinary tract.
Question 2 of 5
Which of the following chemotherapy agents acts by intercalation?
Correct Answer: C
Rationale: Doxorubicin intercalates DNA, inhibiting nucleic acid synthesis.
Question 3 of 5
The most important reason for using a combination of chemotherapeutic agents in the treatment of tuberculosis is
Correct Answer: B
Rationale: Preventing resistance is the primary reason for TB combination therapy, targeting different bacterial populations.
Question 4 of 5
According to the currect WHO guidelines new (untreated) sputum smear positive cases of pulmonary tuberculosis are to be treated with the following regimen
Correct Answer: C
Rationale: WHO guidelines recommend 2 months of isoniazid, rifampin, pyrazinamide, and ethambutol/streptomycin, followed by 4 months of isoniazid and rifampin.
Question 5 of 5
Mycobat tuberculosis infection in a HI V infected patient is treated with
Correct Answer: B
Rationale: HIV patients with TB often receive 4 first-line drugs for 2 months, followed by a 7-month continuation phase due to higher relapse risk.