N. Meningitidis grows on

Correct Answer: D

Rationale: The correct answer is D: Chocolate agar. Neisseria meningitidis is a fastidious organism that requires enriched media for growth. Chocolate agar contains heat-treated blood that provides essential nutrients for the growth of N. meningitidis. The other choices, A: Levine agar, B: Lowenstein-Jensen agar, and C: TCBS agar, do not provide the specific nutrients required for the growth of N. meningitidis. Therefore, only choice D, Chocolate agar, supports the growth of N. meningitidis due to its enriched composition.

Correct Answer: D

Rationale: The correct answer is D, chemotherapy combined with surgical therapy. Actinomycosis is a bacterial infection that requires a combination of antibiotics to target the bacteria and surgery to remove abscesses or infected tissues. Antibiotics alone may not penetrate abscesses effectively. Waiting for self-clearance can lead to complications. Surgical treatment alone may not eradicate the infection entirely. Therefore, the most effective therapeutic plan is to combine chemotherapy to treat the infection systemically and surgery to remove localized infections.

Correct Answer: A

Rationale: Step-by-step rationale for choice A being correct: 1. Parvovirus B19 is a single-stranded DNA (ssDNA) virus. 2. The prefix "parvo-" indicates small size, characteristic of ssDNA viruses. 3. ssDNA viruses replicate in the host cell by converting their ssDNA genome into double-stranded DNA (dsDNA). 4. Therefore, the correct answer is A: Its genome consists of dsDNA. Summary of why other choices are incorrect: B: Parvovirus B19 is a non-enveloped virus, making choice B incorrect. C: Parvovirus B19 has a linear ssDNA genome, not segmented, making choice C incorrect. D: Parvovirus B19 has two structural proteins - VP1 and VP2, making choice D incorrect.

Correct Answer: D

Rationale: The correct answer is D: Hypersensitivity of delayed type. The symptoms described occur 5-10 days after exposure to the antigen, consistent with a delayed hypersensitivity reaction. This type of reaction involves T cells and is characterized by cell-mediated immune response, leading to inflammation and tissue damage. Choices A, B, and C are incorrect because they are associated with different mechanisms of allergic reactions. Immunocomplex reactions (choice A) involve antigen-antibody complexes depositing in tissues, immediate hypersensitivity reactions (choice B) involve IgE-mediated mast cell degranulation, and cytotoxic reactions (choice C) involve antibodies targeting specific cells for destruction.

Correct Answer: A

Rationale: The correct answer is A: Pseudomonas aeruginosa. P. aeruginosa is a Gram-negative rod that is a lactose non-fermenter commonly associated with deep tissue infections. It is an opportunistic pathogen known for its ability to cause infections in immunocompromised individuals. P. aeruginosa is often resistant to multiple antibiotics and can form biofilms, making it difficult to treat. Summary of why other choices are incorrect: B: Escherichia coli is a Gram-negative rod that ferments lactose and is commonly found in the gastrointestinal tract. It is not typically associated with deep tissue infections. C: Salmonella typhi is a Gram-negative rod that causes typhoid fever, primarily affecting the gastrointestinal system, not deep tissue infections. D: Shigella dysenteriae is a Gram-negative rod that causes bacillary dysentery, which primarily affects the gastrointestinal tract and does not typically cause deep tissue infections.

Correct Answer: A

Rationale: Neisseria gonorrhoeae is the correct answer because it is the specific bacterium responsible for causing gonorrhea. It is a sexually transmitted infection that primarily affects the genital tract. Neisseria gonorrhoeae is transmitted through sexual contact and can lead to symptoms such as painful urination, discharge, and pelvic pain. Chlamydia trachomatis (Choice B) is another sexually transmitted bacterium, but it causes chlamydia, not gonorrhea. Mycobacterium tuberculosis (Choice C) is responsible for tuberculosis, a different infectious disease that primarily affects the lungs. Treponema pallidum (Choice D) causes syphilis, another sexually transmitted infection that presents with distinct symptoms from gonorrhea. Therefore, Neisseria gonorrhoeae is the correct choice for causing gonorrhea due to its specific association with this particular infection.

Correct Answer: C

Rationale: The correct answer is C: green monkeys. The Marburg virus was first identified in 1967 in Marburg and Frankfurt, Germany, after outbreaks in lab workers exposed to infected African green monkeys. These monkeys were imported from Uganda. The virus is believed to be originally endemic in certain species of African bats and is transmitted to humans through contact with infected animals. Choice A, laboratory rats, is incorrect as the virus did not originate from rats. Choice B, birds, and Choice D, wild turkeys, are also incorrect as there is no evidence linking these animals to the transmission of the Marburg virus.

Correct Answer: A

Rationale: Step-by-step rationale: 1. Adenoviruses are DNA viruses, so choices B and C (ssRNA and DNA) are incorrect. 2. Adenoviruses have a middle-sized, naked icosahedral capsid, making choice A the correct description. 3. Choice D is incorrect as adenoviruses do have specific characteristics, making "None of the above" an inaccurate option. In summary, the correct answer A is supported by the fact that adenoviruses have a middle-sized, naked icosahedral capsid and contain double-stranded DNA. Choices B, C, and D are incorrect as they do not align with the characteristics of adenoviruses.

Correct Answer: A

Rationale: The correct answer is A because the NSP4 nonstructural protein of rotaviruses indeed acts in a toxic-like manner by disrupting calcium homeostasis, leading to diarrhea. Choice B is incorrect as rotaviruses can cause significant disease in infants, but not typically in adults. Choice C is incorrect as rotaviruses are resistant to stomach acid. Choice D is incorrect as rotaviruses cause a net secretion of water and loss of ions, contributing to diarrhea.