ATI RN
Pediatric Immunization NCLEX Questions Quizlet Questions
Question 1 of 5
Mutations in TAP-1 or TAP-2 may alter the function of the heterodimer TAP. Which of the following is common for patients with TAP mutations?
Correct Answer: C
Rationale: TAP mutations impair MHC Class I antigen presentation, leading to increased susceptibility to upper respiratory infections due to reduced CD8+ T cell responses.
Question 2 of 5
Important role in allergic response; heparin & histamine
Correct Answer: C
Rationale: Basophils release histamine and heparin in allergic responses.
Question 3 of 5
In the adult, the primary lymphoid organs, whose cells expand clonally, are the and secondary lymphoid organs, which create effector cells, are the , as well as mucosa associated lymphoid tissue (MALT) lining the respiratory, GI, and reproductive tracts.
Correct Answer: B
Rationale: Primary lymphoid organs are bone marrow and thymus; secondary are spleen, lymph nodes, and MALT.
Question 4 of 5
Regarding mucosa-associated lymphoid tissue (MALT), which of the following is secreted by B cells across the epithelium?
Correct Answer: A
Rationale: IgA is the primary antibody secreted across mucosal epithelium.
Question 5 of 5
During B cell development, when is there rearrangement in the heavy (H) chain of the immunoblobulin gene started?
Correct Answer: A
Rationale: Heavy chain rearrangement begins in the pro-B cell stage.