Most potent agent increasing capillary permeability is

Correct Answer: C

Rationale: The correct answer is C: PAF. Platelet-activating factor (PAF) is the most potent agent increasing capillary permeability due to its ability to induce endothelial cell contraction and disruption of tight junctions. PAF also activates mast cells to release histamine, further enhancing vascular permeability. LTD4 can also increase capillary permeability but is less potent than PAF. PGD2 and TXA2 do not directly increase capillary permeability.

Correct Answer: A

Rationale: The correct answer is A: Prostaglandins. Prostaglandins are known to induce uterine contractions, playing a crucial role in the process of labor. They stimulate smooth muscle contraction, including that of the uterus, leading to the initiation and progression of labor. Thromboxanes are involved in platelet aggregation, not uterine contractions. Leukotrienes are associated with inflammation and immune responses, not uterine contractions. NSAIDs inhibit prostaglandin synthesis, therefore, they would not cause uterine contractions.

Correct Answer: C

Rationale: The correct answer is C: Intravenous or Intramuscular route. Ketamine can be administered via both intravenous and intramuscular routes due to its rapid onset of action and versatility in different clinical settings. Intravenous administration allows for a quick and precise dosing, ideal for surgical procedures, while intramuscular administration provides an alternative for patients who cannot receive IV medications. Option A and B are incorrect as they are limited to only one route of administration each. Option D is incorrect as ketamine can indeed be administered by one of the mentioned routes.

Correct Answer: A

Rationale: The correct answer is A: Imipramine hydrochloride. Imipramine is a tricyclic antidepressant that is also used to treat childhood enuresis. It works by affecting neurotransmitters in the brain, helping to control the bladder and reduce bedwetting. Imipramine pamoate is a similar drug but is not typically used for enuresis in children. Therefore, choice B is incorrect. Choice C is incorrect because only imipramine hydrochloride is specifically indicated for childhood enuresis. Choice D is incorrect as imipramine hydrochloride is indeed used for this condition.

Correct Answer: D

Rationale: The correct answer is D: All of the above. Opioid analgesics are primarily used for pain relief by acting on the central nervous system to reduce the perception of pain. They can also help suppress cough reflex, making them useful in some cough suppressants. Opioids can also slow down intestinal motility, which can help alleviate diarrhea. Therefore, the correct answer is D as opioids can provide symptomatic relief for pain, cough, and diarrhea. Choices A, B, and C are incorrect because they do not encompass the full range of symptomatic relief that opioids can provide.