ATI RN
Pediatric Immune Disorder Test Questions Questions
Question 1 of 5
Most common cause of secondary immunodeficiency?
Correct Answer: A
Rationale: Protein malnutrition is the most common cause of secondary immunodeficiency globally, as it impairs the production of immune cells and antibodies.
Question 2 of 5
The currently available vaccine to prevent hepatitis A infection is...?
Correct Answer: C
Rationale: The hepatitis A vaccine is an inactivated (killed) virus vaccine, providing immunity without risk of infection.
Question 3 of 5
Atopic people produce an increased amount of IgE. Of the following, which is the most likely explanation for the increased amount of IgE?
Correct Answer: D
Rationale: IL-4 from Th2 cells drives B cells to produce IgE, a key factor in atopy and allergic responses.
Question 4 of 5
The most likely diagnosis in the patient described in Question 2 is
Correct Answer: C
Rationale: Chronic granulomatous disease (CGD) is indicated by recurrent infections with catalase-positive organisms like Staphylococcus aureus, including lymphadenitis and liver abscesses, due to defective phagocyte function. Bruton agammaglobulinemia involves B-cell defects, AIDS is a T-cell disorder, and Kostmann disease is severe congenital neutropenia, none of which fit this presentation as well as CGD.
Question 5 of 5
Matching: Immunodeficiency - Chromosome 22q12
Correct Answer: A
Rationale: DiGeorge syndrome is caused by a 22q11.2 deletion (often written as 22q12 in shorthand), affecting thymic development. No other listed condition matches this chromosomal defect.