ATI RN
ATI Pharmacology Proctored Exam 2024 Quizlet Questions
Question 1 of 5
Most β blockers:
Correct Answer: A
Rationale: Most beta-blockers (e.g., propranolol, metoprolol) have half-lives of 3-10 hours, a true statement reflecting their typical duration, useful for dosing frequency. They have a large, not small, volume of distribution due to tissue penetration, so that's false. Many have good oral bioavailability, not poor, especially non-selective ones. Lipid solubility varies (e.g., propranolol is high, atenolol low), but many cross the BBB, causing CNS effects, though not universally true. They're often metabolized, not excreted unchanged. The half-life range is a key pharmacokinetic feature, guiding their use in hypertension or angina.
Question 2 of 5
What is the Therapeutic Effects of Lithium?
Correct Answer: A
Rationale: Lithium is commonly used as a mood stabilizer in the treatment of bipolar disorder. One of its main therapeutic effects is its ability to prevent or decrease the incidence of acute manic episodes in individuals with bipolar disorder. Lithium can help stabilize mood swings and reduce the severity and frequency of manic episodes. By regulating neurotransmitter levels in the brain, lithium helps to balance mood and prevent the extreme highs associated with mania. It is an essential medication for managing bipolar disorder and is particularly effective in treating manic symptoms.
Question 3 of 5
The nurse is reviewing factors that influence pharmacokinetics in the neonatal patient. Which factor puts the neonatal patient at risk with regard to drug therapy?
Correct Answer: A
Rationale: Neonates have an immature renal system, which affects the excretion of drugs and their metabolites. This immaturity can lead to prolonged drug half-lives and an increased risk of toxicity. While hyperperistalsis, irregular temperature regulation, and smaller circulatory capacity can influence drug therapy, the immature renal system is the most significant factor. Nurses must consider this when administering medications to neonates and adjust dosages accordingly to ensure safety and efficacy.
Question 4 of 5
Most β blockers:
Correct Answer: A
Rationale: Most beta-blockers (e.g., propranolol, metoprolol) have half-lives of 3-10 hours, a true statement reflecting their typical duration, useful for dosing frequency. They have a large, not small, volume of distribution due to tissue penetration, so that's false. Many have good oral bioavailability, not poor, especially non-selective ones. Lipid solubility varies (e.g., propranolol is high, atenolol low), but many cross the BBB, causing CNS effects, though not universally true. They're often metabolized, not excreted unchanged. The half-life range is a key pharmacokinetic feature, guiding their use in hypertension or angina.
Question 5 of 5
A client has been prescribed testosterone. Which medication education should the nurse provide?
Correct Answer: A
Rationale: Testosterone patches require placement on hair-free skin to ensure proper adhesion and absorption, as hair can block drug delivery, reducing efficacy. Active areas like the thigh or arm are suitable if hairless and dry, contrary to avoidance claims-rotation across such sites is standard. Patches are changed daily, not weekly, for consistent hormone levels. Rash observation is key due to potential skin irritation, a common side effect. Hair-free placement is critical education, directly impacting bioavailability, unlike timing or site activity, which follow secondary guidelines, ensuring effective therapy for hypogonadism or related conditions.