ATI RN
Basic principles of pharmacology Questions
Question 1 of 5
Monitoring plasma/serum drug concentrations of the following drugs is recognized as a valuable supplement to clinical monitoring:
Correct Answer: C
Rationale: Gentamicin (C) benefits from plasma monitoring (e.g., peak/trough) due to its narrow therapeutic index and renal clearance, guiding dosing in infections. Carbamazepine (original E, assumed typo) and lithium (D) are monitored too, but C is chosen. Warfarin (B) uses INR, not plasma levels. Carbimazole (A) relies on clinical/thyroid function. Monitoring, critical in aminoglycoside therapy, prevents toxicity (e.g., ototoxicity), a key pharmacokinetic tool.
Question 2 of 5
The following drugs do not readily cross to the CNS
Correct Answer: D
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 3 of 5
The following is Wrong concerning biotransformation phase I reactions
Correct Answer: E
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 4 of 5
Regarding 'first-order kinetics', the following is Wrong:
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 5 of 5
Can be calculated by dividing rate of elimination by drug concentration
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.