Monitoring plasma/serum drug concentrations of the following drugs is recognized as a valuable supplement to clinical monitoring:

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Basic principles of pharmacology Questions

Question 1 of 5

Monitoring plasma/serum drug concentrations of the following drugs is recognized as a valuable supplement to clinical monitoring:

Correct Answer: C

Rationale: Gentamicin (C) benefits from plasma monitoring (e.g., peak/trough) due to its narrow therapeutic index and renal clearance, guiding dosing in infections. Carbamazepine (original E, assumed typo) and lithium (D) are monitored too, but C is chosen. Warfarin (B) uses INR, not plasma levels. Carbimazole (A) relies on clinical/thyroid function. Monitoring, critical in aminoglycoside therapy, prevents toxicity (e.g., ototoxicity), a key pharmacokinetic tool.

Question 2 of 5

The following drugs do not readily cross to the CNS

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 3 of 5

The following is Wrong concerning biotransformation phase I reactions

Correct Answer: E

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 4 of 5

Regarding 'first-order kinetics', the following is Wrong:

Correct Answer: A

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 5 of 5

Can be calculated by dividing rate of elimination by drug concentration

Correct Answer: A

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

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