Migraine is a disorder connected with:

Correct Answer: C

Rationale: The correct answer is C: Dysfunction of regulation of cerebral vessel tonus. Migraine is a neurological disorder characterized by recurrent headaches. The underlying cause is believed to involve abnormal brain activity and the dysfunction of regulating cerebral vessel tonus, leading to vasodilation and inflammation. Thrombosis of cerebral vessels (choice A), brain hemorrhage (choice B), and malignant growth in the brain (choice D) are not directly associated with the pathophysiology of migraine.

Correct Answer: A

Rationale: Prednisolone is the correct answer because it does not contain any fluoride atoms in its chemical structure. Prednisolone is a synthetic corticosteroid that lacks fluorine atoms, making it safer for long-term use compared to other glucocorticoids like dexamethasone, fluocinolone, and triamcinolone, which all contain fluorine atoms. Fluorine atoms in glucocorticoids can increase their potency but also lead to potential adverse effects, such as bone density loss and increased risk of fractures. Therefore, prednisolone is the safest option among the choices provided.

Correct Answer: D

Rationale: Rationale: Histamine H1 antagonists are commonly used to prevent or treat allergic reactions like rhinitis and urticaria due to their antihistaminic properties. They are also effective in managing symptoms of motion sickness and vestibular disturbances by inhibiting histamine release in the brain. Moreover, these antagonists are recommended for treating nausea and vomiting in pregnancy, commonly known as "morning sickness," as they help alleviate these symptoms by blocking histamine receptors. Therefore, the correct answer is D, as histamine H1 antagonists are indicated for all the mentioned conditions. Choices A, B, and C are incorrect as they individually do not encompass the full range of indications for histamine H1 antagonists.

Correct Answer: C

Rationale: The correct answer is C. Vitamin E is not specifically required for the synthesis of prothrombin and clotting factors. A: True. Vitamin E is a vital antioxidant protecting cell membranes from damage. B: True. Vitamin E is known for its antisterility and antiabortion properties. D: True. Vitamin E is essential for regulating oxidative processes. In summary, vitamin E does not play a direct role in the synthesis of clotting factors, making statement C incorrect.

Correct Answer: A

Rationale: The correct answer is A: TRUE. The Coronary Primary Prevention Trial (CPPT) indeed showed that treatment with a lipid-lowering drug reduced the risk of death due to coronary heart disease. This conclusion is based on the findings and results of the study, which have been scientifically validated. Choice B is incorrect because the CPPT did demonstrate the effectiveness of lipid-lowering drugs in reducing coronary heart disease mortality. Choice C, All, and Choice D, None, are also incorrect as they do not accurately reflect the specific outcome of the CPPT. Thus, the correct answer is A because it aligns with the established evidence and results of the study.