Microscopical examination of an infiltrate removed from the submandibular skin area of a 30 y.o. man revealed foci of purulent fluxing surrounded by maturing granulations and mature connective tissue, the pus contains druses consisting of multiple short rod-like elements with one end attached to the homogenous centre. What disease is it?

Correct Answer: A

Rationale: The correct answer is A: Actinomycosis. This is supported by the presence of purulent foci with druses consisting of short rod-like elements attached to a homogenous center, which is characteristic of Actinomyces species. Actinomycosis commonly presents with granulation tissue and connective tissue formation. B: Tuberculosis does not typically present with druses containing short rod-like elements. C: Syphilis does not typically present with purulent foci or druses. D: Candidosis does not typically present with the described features of purulent fluxing and druses with short rod-like elements.

Correct Answer: A

Rationale: The correct answer is A: 20 minutes. Escherichia coli has a short generation time, typically around 20 minutes. This means that under ideal conditions, one bacterium can divide and produce two daughter cells every 20 minutes. This rapid growth rate is a characteristic of E. coli and is important in various fields such as microbiology and biotechnology. Choice B (60 minutes) and Choice C (20 hours) are incorrect as they do not align with the typical generation time of E. coli. Choice D (24 hours) is also incorrect as it is too long for the generation time of E. coli.

Correct Answer: A

Rationale: The correct answer is A: Tetanus. Tetanus is caused by the bacterium Clostridium tetani, which produces a toxin affecting the nervous system. Symptoms such as malaise, irritability, muscular twitching, and high body temperature are characteristic of tetanus due to muscle spasms and rigidity. The 15-day incubation period after trauma aligns with the typical onset of tetanus symptoms. Incorrect choices: B: Anaerobic gas gangrene - This condition usually presents with localized tissue necrosis and gas bubbles in the affected area, not systemic symptoms like malaise and headache. C: Erysipelas - This is a bacterial skin infection presenting with red, swollen patches, not the neurological symptoms seen in tetanus. D: Acute thrombophlebitis - This is a blood clot in a vein causing pain and swelling, not associated with the systemic symptoms and muscle twitching seen in tetanus.

Correct Answer: A

Rationale: The correct answer is A: Actinomycosis. This is supported by the presence of purulent foci with druses consisting of short rod-like elements attached to a homogenous center, which is characteristic of Actinomyces species. Actinomycosis commonly presents with granulation tissue and connective tissue formation. B: Tuberculosis does not typically present with druses containing short rod-like elements. C: Syphilis does not typically present with purulent foci or druses. D: Candidosis does not typically present with the described features of purulent fluxing and druses with short rod-like elements.

Correct Answer: B

Rationale: The optochin sensitivity test is used to differentiate Pneumococcal (Streptococcus pneumoniae) from other streptococci. Optochin sensitivity is a characteristic feature of Pneumococcal, as it inhibits its growth. The test involves placing optochin discs on a culture plate and observing the zone of inhibition around the disc for Pneumococcal. Neisseria gonorrhoeae, Staphylococci, and Group A streptococci do not exhibit optochin sensitivity, making them incorrect choices. In summary, the optochin sensitivity test is specific to Pneumococcal, making choice B the correct answer.

Correct Answer: D

Rationale: The correct answer is D (All of the above) because different bacteria can cause pneumonia. Streptococcus pneumoniae is the most common cause of community-acquired pneumonia. Mycobacterium tuberculosis causes tuberculosis, which can lead to pneumonia. Pseudomonas aeruginosa is a common cause of hospital-acquired pneumonia. Therefore, all three bacteria can be responsible for causing pneumonia in different contexts. Choices A, B, and C are incorrect because each bacterium individually can cause pneumonia, so selecting only one option would not cover the full spectrum of bacterial causes of pneumonia.

Correct Answer: A

Rationale: The correct answer is A because a soft chancre is a type of sexually transmitted infection caused by the bacterium Haemophilus ducreyi. It presents as a painless ulcer on the genitals. The other choices are incorrect. B is incorrect because STIs can enter the body through various routes, not only the urogenital tract mucosa. C is incorrect because immunity to syphilis is not lifelong; reinfection is possible. D is incorrect because STIs can occur in any country regardless of social status or hygiene levels.

Correct Answer: D

Rationale: The correct answer is D: All of the above. 1. Escherichia coli can produce endotoxin due to its lipopolysaccharide component. 2. Salmonella enterica also produces endotoxin as part of its cell wall structure. 3. Pseudomonas aeruginosa is known to produce endotoxin as well. Therefore, all of these bacteria are capable of producing endotoxin, which can trigger an excessive immune response leading to septic shock. Other choices are incorrect because they do not cover all the bacteria mentioned in the question that are capable of producing endotoxin.

Correct Answer: A

Rationale: The correct answer is A: Gp120. Gp120 is a glycoprotein on the surface of the HIV virus that specifically binds to the CD4 receptor on target cells. This binding is essential for the virus to enter the host cell and initiate the infection process. Gp41 is another glycoprotein on the virus that helps with membrane fusion, not binding to CD4. Gp32 and Gp55 are not involved in the specific binding of HIV to CD4 molecules. So, A is correct as it directly plays a key role in the initial attachment of HIV to target cells.