Microscopic analysis of tissue sampling from affected area of mucous membrane of oral cavity revealed bacillus in form of accumulations that looked like a pack of cigarettes. Ziehl-Neelsen staining gives them red colour. What kind of pathogenic organism was most likely revealed in tissue sampling?

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Microbiology A Systems Approach Test Bank Questions

Question 1 of 9

Microscopic analysis of tissue sampling from affected area of mucous membrane of oral cavity revealed bacillus in form of accumulations that looked like a pack of cigarettes. Ziehl-Neelsen staining gives them red colour. What kind of pathogenic organism was most likely revealed in tissue sampling?

Correct Answer: B

Rationale: The correct answer is B: M.tuberculosis. The description of bacillus in the form of accumulations resembling a pack of cigarettes and staining red with Ziehl-Neelsen staining is characteristic of Mycobacterium tuberculosis. M.leprae (Choice A) is associated with leprosy and does not typically appear as described. A.bovis (Choice C) is a type of Mycobacterium but is not typically found in the oral cavity. A.israilii (Choice D) is not associated with the characteristics mentioned in the question. Therefore, based on the specific characteristics described, M.tuberculosis is the most likely pathogenic organism revealed in the tissue sampling.

Question 2 of 9

When doctors of a sanitary and epidemiologic institution examine employees of public catering establishments they often reveal asymptomatic parasitosis, that is when a healthy person is a carrier of cysts that infect other people. What causative agent can parasitize in such a way?

Correct Answer: A

Rationale: The correct answer is A: Dysenteric amoeba. This is because dysenteric amoebas can cause asymptomatic parasitosis, where a healthy person carries cysts that can infect others. Dysenteric amoebas are known to infect the intestines and can be transmitted through contaminated food or water. Choice B, Malarial plasmodium, causes malaria transmitted through mosquitoes. Choice C, Enteral trichomonad, causes diarrhea and is transmitted through contaminated water. Choice D, Dermatotropic leishmania, causes skin lesions and is transmitted through sandfly bites. These choices do not fit the scenario of asymptomatic parasitosis in public catering establishments.

Question 3 of 9

The specific prevention (by vaccination) of the disease gas gangrene (caused by Clostridium perfringens) is based on:

Correct Answer: B

Rationale: The correct answer is B: Anatoxin. An anatoxin is a toxin that has been rendered harmless while retaining its ability to stimulate an immune response. Gas gangrene is caused by the toxins produced by Clostridium perfringens, not the bacteria itself. Therefore, vaccination with an anatoxin can trigger the immune system to produce antibodies against the toxin, providing immunity against the disease. A: Killed whole cell vaccine - Gas gangrene is caused by toxins, not the whole bacterium. This type of vaccine may not be effective in preventing the disease. C: There is no specific prevention by vaccination - This is incorrect, as vaccination with an anatoxin can prevent gas gangrene. D: Alive attenuated vaccine - Attenuated vaccines contain live, weakened forms of the pathogen. However, for gas gangrene prevention, targeting the specific toxin with an anatoxin vaccine is more appropriate.

Question 4 of 9

What is the name of the enzyme that allows the bacteria to become resistant to most penicillins?

Correct Answer: C

Rationale: The correct answer is C: Beta lactamase. This enzyme is produced by bacteria to break down the beta-lactam ring structure of penicillins, rendering them ineffective. Beta lactam ring (A) is part of the penicillin molecule, not an enzyme. MRSA (B) stands for methicillin-resistant Staphylococcus aureus, a type of bacteria resistant to certain antibiotics, not an enzyme. Aminoglycoside ring (D) refers to a different class of antibiotics and is not related to penicillin resistance in bacteria.

Question 5 of 9

A patient with convulsive contractions of facial muscles was admitted to the infectious disease ward. From a scratch on his lower right extremity analysts isolated bacteria with terminal endospores that gave them drumstick appearance. What bacteria are compliant with given description?

Correct Answer: A

Rationale: Step-by-step rationale for the correct answer (A - Clostridium tetani): 1. The patient has convulsive contractions of facial muscles, indicating tetanus. 2. Isolation of bacteria with terminal endospores that have a drumstick appearance is characteristic of Clostridium tetani. 3. Clostridium tetani produces tetanospasmin toxin causing muscle spasms. 4. Therefore, the correct answer is Clostridium tetani (A). Summary of why other choices are incorrect: B: Clostridium botulinum causes botulism, not tetanus. C: Clostridium perfringens causes gas gangrene, not tetanus. D: Bacillus anthracis causes anthrax, not tetanus.

Question 6 of 9

The branch of pharmacology that addresses drug amounts at various sites in the body after drug administration is called:

Correct Answer: B

Rationale: The correct answer is B: pharmacokinetics. Pharmacokinetics is the study of drug movement in the body, including absorption, distribution, metabolism, and excretion. It focuses on how the body processes a drug over time. Pharmacodynamics (A) is the study of the effects drugs have on the body. Pharmacotherapeutics (C) involves using drugs to treat diseases. Pharmacy (D) is the practice of preparing and dispensing medications. Pharmacokinetics specifically deals with drug concentrations at different body sites after administration, making it the most appropriate choice for this question.

Question 7 of 9

Which of the following bacteria is known for producing a capsule that helps it avoid the immune system?

Correct Answer: A

Rationale: The correct answer is A: Streptococcus pneumoniae. This bacterium is known for producing a capsule that helps it evade the immune system. The capsule acts as a protective barrier, making it difficult for the immune system to recognize and attack the bacteria. Streptococcus pneumoniae is a common cause of pneumonia and meningitis. Explanation for why other choices are incorrect: B: Escherichia coli does not typically produce a capsule for immune evasion. It is more commonly associated with gastrointestinal infections. C: Salmonella enterica also does not produce a capsule for immune evasion. It is known for causing foodborne illness. D: Bacillus subtilis is a soil bacterium that is not known for producing a capsule to avoid the immune system.

Question 8 of 9

Which bacteria is a common cause of urinary tract infections (UTIs)?

Correct Answer: B

Rationale: The correct answer is B: Escherichia coli. E. coli is the most common cause of UTIs due to its ability to colonize the urinary tract. It possesses adhesive factors that enable it to attach to the bladder and cause infection. Clostridium tetani causes tetanus, Mycobacterium leprae causes leprosy, and Bacillus anthracis causes anthrax, none of which are typically associated with UTIs. E. coli's prevalence in the gut and its pathogenic mechanisms make it the leading cause of UTIs.

Question 9 of 9

A patient complains of acute spastic abdominal pain, frequent urge to defecate, liquid bloody feces with mucus. Laboratory analysis of fecal smear revealed inconstant in shape organisms with erythrocyte. What is the most likely diagnosis?

Correct Answer: A

Rationale: The correct answer is A: Amebiasis. Amebiasis is caused by the parasite Entamoeba histolytica, presenting with symptoms like acute abdominal pain, bloody diarrhea with mucus, and inconstant shape organisms seen in fecal smear. The presence of erythrocytes supports the diagnosis due to the parasite's ability to invade intestinal mucosa causing bleeding. Choice B (Lambliasis) presents with different symptoms like steatorrhea and fatigue. Choice C (Schistosomiasis) is mainly associated with liver and urinary symptoms. Choice D (Intestinal trichomoniasis) commonly presents with watery diarrhea and does not typically cause bloody stools. Therefore, based on the patient's symptoms and fecal smear findings, Amebiasis is the most likely diagnosis.

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