ATI RN
ATI Proctored Pharmacology Quizlet Questions
Question 1 of 5
Metronidazole is effective in the treatment of ____ (select all that apply)
Correct Answer: A
Rationale: Metronidazole is a versatile antibiotic that is effective in the treatment of various infections caused by anaerobic bacteria and parasites.
Question 2 of 5
Which of the following is the antidote of first choice in the treatment of potentially fatal paracetamol overdose?
Correct Answer: B
Rationale: Paracetamol overdose risks fatal hepatotoxicity via NAPQI, a toxic metabolite depleting glutathione. Methionine replenishes glutathione orally, effective if given early, but less preferred due to slower action and GI upset. Acetylcysteine, administered IV or orally, directly supplies glutathione precursors, neutralizing NAPQI within the critical 8-12 hour window, making it the first-choice antidote per global guidelines (e.g., Rumack-Matthew nomogram). It's superior for its rapid efficacy, especially beyond 8 hours, preventing liver failure. Naloxone reverses opioids, irrelevant here. Dicobalt edetate treats cyanide poisoning, not paracetamol. Flumazenil targets benzodiazepines. Acetylcysteine's mechanism and timing flexibility ensure maximal survival, critical in emergency settings where overdose severity varies.
Question 3 of 5
Which statement is accurate regarding attention-deficit hyperactivity disorder (ADHD)?
Correct Answer: B
Rationale: ADHD in girls often presents as anxiety/withdrawal, versus boys' hyperactivity-per research-though diagnosis favors boys. It's not bipolar-mania/depression differ. Boys dominate diagnosis stats. It's early, not late, onset. Gender presentation accuracy reflects ADHD nuance.
Question 4 of 5
While assessing a patient who is receiving intravenous digitalis, the nurse recognizes that the drug has a negative chronotropic effect. How would this drug effect be evident in the patient?
Correct Answer: B
Rationale: Digitalis has a negative chronotropic effect, meaning it slows down the heart rate. This can be evident in a patient by observing a decrease in their heart rate. Chronotropy refers to the heart rate or rhythm of the heart. Digitalis works by inhibiting the sodium-potassium pump in the heart muscle cells, leading to an increase in intracellular calcium levels. This results in a decreased heart rate and improved contractility of the heart muscle. Therefore, a decreased heart rate is the expected effect when a patient is receiving intravenous digitalis.
Question 5 of 5
Which of the following agents may cause tremors as a side effect and, thus, should be used with caution in patients with Parkinson's disease, even though it is also indicated for the treatment of dementia associated with Parkinson's disease?
Correct Answer: C
Rationale: Rivastigmine, an acetylcholinesterase inhibitor, treats Parkinson's disease dementia by enhancing cholinergic function, improving cognition. However, increased acetylcholine can exacerbate tremors, a core Parkinson's symptom, by disrupting dopamine-acetylcholine balance in the basal ganglia, requiring cautious use. Benztropine, an anticholinergic, reduces tremors, not causes them. Rotigotine, a dopamine agonist, improves motor symptoms. Dimethyl fumarate manages MS, not Parkinson's dementia, and lacks tremor association. Rivastigmine's benefit in dementia must be weighed against its potential to worsen tremors, making it the drug needing careful monitoring in this context.