Metoprolol is a cardioselective beta blocker (relatively selective beta1 - blocker)

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Question 1 of 5

Metoprolol is a cardioselective beta blocker (relatively selective beta1 - blocker)

Correct Answer: C

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 2 of 5

A 46-year-old woman complained of daytime sleepiness after taking an antihistamine for allergic rhinitis. Which of the following brain regions was most likely involved in the adverse effect of this drug?

Correct Answer: D

Rationale: The correct answer is D: Nucleus basalis of Meynert. The antihistamine likely caused sedation by blocking histamine receptors in the brain. The Nucleus basalis of Meynert is responsible for arousal and wakefulness, so blocking histamine receptors there can lead to daytime sleepiness. A: Nucleus tractus solitarius is involved in autonomic functions like blood pressure and heart rate regulation, not sedation. B: Caudatum is part of the basal ganglia involved in motor control and learning, not sedation. C: Hippocampus is crucial for memory and learning, not sedation.

Question 3 of 5

Which of the following adverse effects were most likely to occur during the first days of therapy with sertraline and diazepam?

Correct Answer: C

Rationale: The correct answer is C: Excessive sedation and drowsiness. Sertraline and diazepam are both central nervous system depressants, which can lead to sedation and drowsiness especially during the initial days of therapy due to the body adjusting to the medication. This is a common side effect of these drugs and can impact the individual's alertness and ability to function normally. Rationale: - A: Excitement and irritability are more commonly associated with stimulant medications, not with sertraline and diazepam. - B: Mental confusion and anterograde amnesia are more commonly seen with benzodiazepines like diazepam, but are not typically the main adverse effects during the first days of therapy. - D: Respiratory depression and apnea are serious side effects of central nervous system depressants, but they are not commonly observed during the initial days of therapy with sertraline and diazepam.

Question 4 of 5

Which of the following drugs would be relatively contraindicated for a patient diagnosed with generalized anxiety disorder?

Correct Answer: D

Rationale: The correct answer is D: Diazepam. Diazepam belongs to the benzodiazepine class of drugs, which can be addictive and have a high potential for abuse. For a patient with generalized anxiety disorder, long-term treatment with benzodiazepines like diazepam is generally discouraged due to the risk of tolerance, dependence, and withdrawal symptoms. Other choices (A, B, C) are commonly used for treating anxiety disorders without the same level of addiction potential as diazepam. Venlafaxine is an SNRI, Buspirone is a non-addictive anxiolytic, and Paroxetine is an SSRI.

Question 5 of 5

Which of the following was most likely the disorder suffered by the patient's father?

Correct Answer: B

Rationale: The correct answer is B: Malignant hyperthermia. This disorder is characterized by a severe reaction to certain anesthesia drugs, leading to muscle rigidity, high fever, and potentially life-threatening complications. The patient's father likely experienced this disorder if he had a reaction during surgery. Acute intermittent porphyria (A) presents with abdominal pain and neuropsychiatric symptoms, not hyperthermia. Acute hepatitis (C) involves liver inflammation, not anesthesia reaction. Hemolytic anemia (D) is a condition where red blood cells are destroyed, not related to anesthesia.

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