ATI RN
Chapter 25 Cardiovascular Drugs Quizlet Questions
Question 1 of 5
Metolazone (Mykrox) acts at this nephron site:
Correct Answer: C
Rationale: Metolazone acts at the distal convoluted tubule. It inhibits sodium and chloride reabsorption, leading to increased diuresis. The distal convoluted tubule is where sodium and chloride reabsorption are regulated by aldosterone. Metolazone's mechanism of action aligns with this site, making choice C the correct answer. Choices A, B, and D are incorrect because Metoljson's action is not targeted at the proximal convoluted tubule, ascending thick limb of the loop of Henle, or the collecting duct.
Question 2 of 5
Tick the drug used for amoebiasis treatment:
Correct Answer: B
Rationale: The correct answer is B: Iodoquinol. Iodoquinol is used for amoebiasis treatment due to its effectiveness against the parasite Entamoeba histolytica. It works by disrupting the energy metabolism of the parasite. Nitrofurantoin is an antibiotic primarily used for urinary tract infections. Pyrazinamide is used for tuberculosis treatment. Mefloquine is primarily used for malaria prophylaxis and treatment. Therefore, B is the correct choice for amoebiasis treatment.
Question 3 of 5
Tick the unwanted effects of didanozine:
Correct Answer: D
Rationale: Step-by-step rationale for why choice D is correct: 1. Didanozine is known to cause peripheral neuropathy and pancreatitis as unwanted effects. 2. Hyperuricemia is also a possible side effect of didanozine. 3. Hallucinations, dizziness, insomnia (A) are not typically associated with didanozine. 4. Anemia, neutropenia, nausea (B) are not common side effects of didanozine. 5. Hypertension, vomiting, diarrhea (C) are also not typically linked to didanozine. In summary, choice D is correct because it accurately lists unwanted effects of didanozine, while the other choices do not align with common side effects of this medication.
Question 4 of 5
Which of the following events most likely caused the patient's symptoms?
Correct Answer: B
Rationale: The correct answer is B: Erythromycin-induced increase in digoxin oral bioavailability. Erythromycin inhibits the metabolism of digoxin, leading to increased serum levels and potential toxicity. This explains the patient's symptoms. A: Hydrochlorothiazide-induced hypokalemia may cause weakness, but not specific symptoms related to digoxin toxicity. C: Hydrochlorothiazide-induced hypocalcemia does not directly impact digoxin levels or cause digoxin toxicity symptoms. D: Captopril-induced decrease in digoxin clearance may increase digoxin levels, but not through oral bioavailability like erythromycin.
Question 5 of 5
A 27-year-old woman with a history of high altitude sickness was placed on prophylactic treatment with a diuretic drug prior to going on a hiking trip in the Rocky Mountains. Which of the following urine electrolyte profiles is most consistent with this drug treatment?
Correct Answer: A
Rationale: The correct answer is A: Prole P. The diuretic drug would lead to increased urine volume and electrolyte excretion, resulting in a profile consistent with Prole P, which typically shows decreased urine osmolality, increased urine volume, and increased electrolyte excretion. Choice B, Prole Q, typically shows decreased urine volume and electrolyte excretion, which would not be consistent with diuretic use. Choice C, Prole R, typically shows increased osmolality and decreased volume, which is not in line with diuretic effects. Choice D, Prole S, typically shows normal urine electrolyte values, which would not reflect the impact of a diuretic drug.