ATI RN
ABVD chemotherapy drugs Questions
Question 1 of 5
Methenamine salts are used as urinary antiseptics. The reason why they lack systemic antibacterial action is that they are
Correct Answer: C
Rationale: Methenamine releases formaldehyde, an antiseptic, only in acidic urine (low pH), limiting its action to the urinary tract.
Question 2 of 5
Which of the following drugs enhances GABA actions on the neuromuscular junctions of nematodes and arthropods?
Correct Answer: B
Rationale: Ivermectin enhances GABA activity at nematode and arthropod neuromuscular junctions, causing paralysis and death of the parasite.
Question 3 of 5
Which of the following antimalarial drugs causes a dose-dependent toxic state that includes flushed and sweaty skin, dizziness, nausea, diarrhea, tinnitus, blurred vision, and impaired hearing?
Correct Answer: D
Rationale: Quinine causes cinchonism, a dose-dependent toxicity with symptoms like tinnitus, blurred vision, and nausea.
Question 4 of 5
This drug can clear trypanosomes from the blood and lymph nodes and is active in the late CNS stages of African sleeping sickness.
Correct Answer: B
Rationale: Melarsoprol crosses the blood-brain barrier and is effective against late-stage African trypanosomiasis (sleeping sickness) in the CNS.
Question 5 of 5
In a patient with diffuse lymphoma, the oncologist suggests a treatment strategy that involves the initial administration of doxorubicin to obtain a significant logkill, followed by the cell cycle-specific drugs cytarabine and vincristine. This therapeutic strategy is called
Correct Answer: B
Rationale: Recruitment involves using a non-cycle-specific drug (doxorubicin) to kill a large number of cells, followed by cycle-specific drugs (cytarabine, vincristine) to target remaining cycling cells.