ATI RN
Diabetic drugs Questions
Question 1 of 5
Metformin is preferred over phenformin because
Correct Answer: B
Rationale: Metformin has a lower risk of lactic acidosis than phenformin, though it still requires caution in renal impairment.
Question 2 of 5
Which of the following features disfavors use of oral hypoglycaemics in diabetes mellitus?
Correct Answer: B
Rationale: High insulin needs (>40 U/day) suggest severe disease or type 1 DM, where oral agents are ineffective.
Question 3 of 5
Select the drug which tends to reverse insulin resistance by increasing cellular glucose transporters.
Correct Answer: B
Rationale: Troglitazone (a thiazolidinedione) enhances insulin sensitivity by increasing GLUT4 transporters.
Question 4 of 5
Nephrogenic diabetes insipidus is seen with
Correct Answer: A
Rationale: Demeclocycline inhibits ADH action in the kidney, causing nephrogenic diabetes insipidus.
Question 5 of 5
Diabetic ketoacidosis is best managed by
Correct Answer: A
Rationale: IV crystalline (regular) insulin allows rapid correction of hyperglycemia and acidosis in DKA.