Mentzer index of less than 12.5 suggests thalassemia trait, it represents

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ASCP Hematology Questions Questions

Question 1 of 5

Mentzer index of less than 12.5 suggests thalassemia trait, it represents

Correct Answer: A

Rationale: Mentzer index (A) = MCV/RBC; <12.5 indicates thalassemia trait vs. >13 for iron deficiency.

Question 2 of 5

The best treatment option for hereditary spherocytosis is

Correct Answer: A

Rationale: Splenectomy (A) is the definitive treatment for severe hereditary spherocytosis to reduce hemolysis.

Question 3 of 5

Which of the following agents helps in decreasing the frequency of vasoocclusive crises in children with sickle cell disease?

Correct Answer: C

Rationale: Hydroxyurea (C) reduces vaso-occlusive crises by increasing fetal hemoglobin.

Question 4 of 5

Which of the following conditions causes profound thrombocytopenia?

Correct Answer: A

Rationale: DIC (A) consumes platelets, causing profound thrombocytopenia.

Question 5 of 5

One of the following features DOES NOT fit hemophilia A

Correct Answer: B

Rationale: Hemophilia A has normal PT (B incorrect); PTT is prolonged (C) due to low factor VIII (D).

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