Measuring serum concentrations of renin and aldosterone differentiates children with metabolic alkalosis; both renin and aldosterone are elevated in

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Pediatric Musculoskeletal Assessment Questions

Question 1 of 5

Measuring serum concentrations of renin and aldosterone differentiates children with metabolic alkalosis; both renin and aldosterone are elevated in

Correct Answer: A

Rationale: Renovascular disease increases renin and aldosterone due to reduced renal perfusion.

Question 2 of 5

Becker muscular dystrophy (BMD) is a disease that is fundamentally similar to Duchenne muscular dystrophy (DMD). Of the following, the MOST recognized feature of BMD is

Correct Answer: B

Rationale: BMD is distinguished from DMD by longer ambulation time, often into adolescence or adulthood, due to milder dystrophin dysfunction.

Question 3 of 5

All the following myopathies are characterized by proximal muscle wasting EXCEPT

Correct Answer: D

Rationale: Central core myopathy typically presents with mild weakness and hypotonia rather than significant proximal muscle wasting, unlike the muscular dystrophies listed.

Question 4 of 5

The MOST definitive diagnostic test in Werdnig-Hoffmann disease is

Correct Answer: D

Rationale: Molecular genetic testing for SMN1 gene deletion is the definitive diagnostic test for Werdnig-Hoffmann disease (SMA type 1).

Question 5 of 5

In Guillain-Barré syndrome, the onset is gradual and progresses over days or weeks. The maximal severity of weakness is usually reached by

Correct Answer: B

Rationale: In GBS, maximal weakness typically peaks by 4 weeks, per diagnostic criteria, though it varies.

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