Matching: Red blood cell aplasia - Rarely needs multiple transfusions

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Question 1 of 5

Matching: Red blood cell aplasia - Rarely needs multiple transfusions

Correct Answer: B

Rationale: Transient erythroblastopenia of childhood (B) often resolves without frequent transfusions.

Question 2 of 5

Matching: For each of the following disorders, select the appropriate platelet presentation - Wiskott-Aldrich

Correct Answer: A

Rationale: Wiskott-Aldrich (A) features thrombocytopenia with small platelets.

Question 3 of 5

A 10-year-old undergoes total splenectomy because of trauma. The best statement about the risk of postsplenectomy infection is that

Correct Answer: D

Rationale: Splenectomy increases lifelong infection risk (E), especially from encapsulated organisms like pneumococci, not reliably prevented by splenosis (C) or vaccines (D) alone.

Question 4 of 5

The definitive diagnostic test for the condition described in Question 19 is

Correct Answer: D

Rationale: Osmotic fragility test (E) confirms hereditary spherocytosis by showing RBC fragility.

Question 5 of 5

A 3.2-kg, 40-week's-gestational age male is born by spontaneous vaginal delivery to a 20-year-old white female. Past maternal medical problems reveal a history of easy bruising that required splenectomy at 18 years of age. Current coagulation studies of the mother include a prothrombin time of 12 seconds, a partial thromboplastin time of 25 seconds, fibrinogen of 300 mg/dL, and a platelet count of 175,000. At 3 hours of age, the infant is noted to have multiple petechiae and a platelet count of 15,000. The most likely diagnosis is

Correct Answer: C

Rationale: Maternal ITP (C) with splenectomy history can cause neonatal thrombocytopenia via passive antibody transfer.

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