ATI RN
NCLEX Pediatric Immunization Questions Questions
Question 1 of 5
Matching: Immunodeficiency - Splenomegaly
Correct Answer: C
Rationale: Common variable immunodeficiency (CVID) often presents with splenomegaly due to lymphoid hyperplasia or chronic infections. Bruton and Hyper IgM can also have splenomegaly, but CVID is more commonly associated.
Question 2 of 5
Which of the following is not typically associated with an eosinophilic response and eosinophilia?
Correct Answer: D
Rationale: Pinworms typically cause local irritation without significant eosinophilia, unlike allergies, drug reactions, or parasitic infections like trichinosis.
Question 3 of 5
The major components of host defense include anatomic barriers and the innate and adaptive immune systems. The adaptive immune system is made up of
Correct Answer: A
Rationale: The adaptive immune system specifically involves T and B lymphocytes, which are responsible for cell-mediated and humoral immunity, respectively.
Question 4 of 5
A 15-month-old child presented with repeated skin and pulmonary infections started shortly after birth, his blood film showed severe neutropenia with impressive monocytosis, he is the third sibling of a first cousin healthy parents, the second sibling had the same problem and died due to acute myeloid leukemia. Of the following, the MOST likely diagnosis is
Correct Answer: B
Rationale: Kostmann syndrome (severe congenital neutropenia) presents with severe neutropenia, monocytosis, and leukemia risk, often autosomal recessive.
Question 5 of 5
A 7-year-old child presented with severe stridor and abdominal pain, he gives history of recurrent episodes of nonpruritic edema lasting 48 to 72 hours, which usually triggered by stress, or anxiety. Of the following, the MOST effective treatment is
Correct Answer: A
Rationale: Purified C1-inhibitor replaces the deficient protein in hereditary angioedema, effectively resolving acute episodes.