ATI RN
Pediatric Immunization NCLEX Questions Questions
Question 1 of 5
Matching: Immunodeficiency - Lymphopenia plus severe neutropenia
Correct Answer: C
Rationale: Reticular dysgenesis is a severe condition with both lymphopenia and neutropenia due to failure of lymphoid and myeloid precursors.
Question 2 of 5
A 6-month-old presents with recurrent cellulitis and bacteremias due to Staphylococcus aureus. The white blood cell count is 2500 with 5% neutrophils, 10% eosinophils, 35% monocytes, and 50% lymphocytes. The platelet count is 650,000. A brother and a female cousin died at the age of 18 months and 2 years, respectively. The most likely diagnosis is
Correct Answer: C
Rationale: Kostmann disease (severe congenital neutropenia) fits with persistent neutropenia, recurrent Staphylococcus aureus infections, and a family history suggesting autosomal recessive inheritance.
Question 3 of 5
A 15-month-old male child presented with thrombocytopenic purpura, atopic dermatitis, and recurrent infections caused by cytomegalovirus and P.jiroveci. Immunoglobulin assay revealed elevated IgE and IgA with decreased IgM levels. Of the following, the MOST likely diagnosis is
Correct Answer: A
Rationale: Wiskott-Aldrich syndrome is characterized by eczema, thrombocytopenia, and recurrent infections with abnormal immunoglobulin levels (elevated IgE/IgA, low IgM).
Question 4 of 5
Light microscopy of neutrophils for the presence of giant granules can help to diagnose
Correct Answer: B
Rationale: Giant granules in neutrophils are a hallmark of Chédiak-Higashi syndrome, visible under light microscopy.
Question 5 of 5
which of the following cells will be the last cell to perform its function in skin pathogen invasion
Correct Answer: B
Rationale: Naïve CD8 lymphocytes require activation by antigen-presenting cells and differentiation into cytotoxic T cells, making them the last to act compared to innate cells like NK cells, macrophages, and intraepithelial lymphocytes.