ATI RN
Pediatric Immunizations NCLEX Questions Questions
Question 1 of 5
Matching: Complement deficiency - Recurrent neisserial infection
Correct Answer: A
Rationale: Deficiencies in C5, C6, C7, C8, or C9 impair the membrane attack complex, leading to recurrent Neisseria infections (e.g., meningococcus). Properdin stabilizes the alternative pathway but is less directly linked to neisserial susceptibility compared to terminal complement deficiencies.
Question 2 of 5
The X-linked lymphoproliferative (XLP) syndrome is classically associated with overwhelming infection with which organism?
Correct Answer: A
Rationale: XLP is classically linked to severe, often fatal Epstein-Barr virus infections due to defective immune regulation.
Question 3 of 5
Repeated meningococcal infections suggest what type of immune disorder?
Correct Answer: D
Rationale: Repeated meningococcal infections suggest a complement deficiency, particularly terminal components (C5-9), impairing bacterial lysis.
Question 4 of 5
An 8-month-old infant presented with chronic diarrhea, persistent right ear discharge, oral candidiasis responding poorly to antifungal drugs, and failure to thrive. On examination the infant has exfoliative erythroderma, lymphadenopathy, and hepatosplenomegaly. Peripheral blood showed eosinophilia and elevated IgE. The parents are young first cousin and he is their first baby. Of the following, the MOST likely diagnosis is
Correct Answer: C
Rationale: Omenn syndrome, a form of SCID, presents with erythroderma, eosinophilia, and elevated IgE due to consanguinity-related genetic defects.
Question 5 of 5
Viral infections associated with neutropenia include
Correct Answer: D
Rationale: Hepatitis B is known to cause neutropenia, unlike the other listed viral infections which are less commonly associated.