Matching: Complement deficiency - Nonpitting edema

Questions 60

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Pediatric Immunization NCLEX Questions Quizlet Questions

Question 1 of 5

Matching: Complement deficiency - Nonpitting edema

Correct Answer: D

Rationale: C1 inhibitor deficiency causes hereditary angioedema, characterized by nonpitting edema due to unregulated bradykinin production. Other complement deficiencies do not typically present with this feature.

Question 2 of 5

In addition to recurrent staphylococcal abscesses and elevated serum IgE, the clinical manifestations of hyperimmunoglobulinemia E (hyper-IgE) syndrome frequently include which of the following?

Correct Answer: B

Rationale: Hyper-IgE syndrome commonly includes pneumatoceles (lung cysts) from recurrent pneumonias, alongside staphylococcal abscesses and high IgE.

Question 3 of 5

Long-term treatment of the disease described in Question 27 is best accomplished with

Correct Answer: D

Rationale: Granulocyte colony-stimulating factor (G-CSF) is the mainstay long-term treatment for Kostmann disease, boosting neutrophil production.

Question 4 of 5

An 8-year-old child having coarse facial features seen by dentist because of failure to shed primary teeth and visited an orthopedician due to frequent fractures of lower limbs, now presented with skin abscesses and eczema. Of the following, the MOST likely diagnosis is

Correct Answer: D

Rationale: Hyper-IgE syndrome features coarse facies, retained primary teeth, recurrent fractures, skin abscesses, and eczema due to STAT3 mutations.

Question 5 of 5

C5, C6, C7, and C8 deficiency usually lead to

Correct Answer: A

Rationale: Late complement deficiencies (C5-C8) impair the membrane attack complex, increasing susceptibility to meningococcal infections.

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