ATI RN
ATI Pharmacology Practice A Questions
Question 1 of 5
Mannitol (Osmitrol), an osmotic diuretic, is contraindicated to which conditions? Select all that apply.
Correct Answer: B
Rationale: Mannitol is contraindicated in patients with narrow-angle glaucoma. It can exacerbate the condition by causing an increase in intraocular pressure, leading to potential vision damage or loss. Therefore, caution should be exercised and alternative treatments considered for patients with narrow-angle glaucoma when considering the use of mannitol.
Question 2 of 5
A patient is being discharged on anticoagulant therapy. The nurse will include in the patient- education conversation that it is important to avoid herbal products that contain which substance?
Correct Answer: B
Rationale: Ginkgo is the herbal product to avoid because it can interact with anticoagulant therapy and increase the risk of bleeding. Ginkgo has blood-thinning properties, which can further potentiate the anticoagulant effects of medications like warfarin, increasing the risk of bleeding complications. It's essential for patients on anticoagulant therapy to avoid herbal products containing ginkgo to prevent adverse effects and ensure the effectiveness of their prescribed medication.
Question 3 of 5
Which class of targeted therapy would cause the nurse the most concern in regard to a possible infusion reaction?
Correct Answer: C
Rationale: Monoclonal antibodies, such as trastuzumab and rituximab, are more likely to cause infusion reactions compared to other classes of targeted therapy. These reactions can range from mild symptoms like fever and chills to severe anaphylaxis. Tyrosine kinase inhibitors, multikinase inhibitors, and proteasome inhibitors are less commonly associated with infusion reactions. The nurse should closely monitor patients receiving monoclonal antibodies during infusion and be prepared to manage any adverse reactions promptly.
Question 4 of 5
The nurse plans to teach a class on anabolic steroids to a group of high school athletes. What will the best plan by the nurse include?
Correct Answer: A
Rationale: Anabolic steroids, synthetic testosterone derivatives, suppress natural hormone production, including spermatogenesis, leading to infertility-a critical risk for young athletes to understand. They also impact the entire body, notably causing liver damage (e.g., hepatotoxicity or tumors), a systemic effect worth noting. However, while effective for muscle growth, weight training surpasses steroids in safety and sustainability, debunking the ‘most effective' claim. Aggression, or ‘roid rage,' is a well-documented behavioral change due to hormonal imbalance, making it another key point. Infertility stands out in education, as it's a direct, long-term consequence tied to reproductive health, resonating with teens' future planning, and is supported by evidence of testicular atrophy and reduced sperm count, distinguishing it from broader effects or myths about efficacy.
Question 5 of 5
The nurse is performing a health history on a patient who is ordered to begin therapy with valproic
Correct Answer: D
Rationale: Valproic acid is known to have potential hepatotoxicity, meaning it can damage the liver. Therefore, if a patient already has liver disease, it can increase the risk of further liver damage when taking valproic acid. The nurse needs to be particularly cautious when a patient with pre-existing liver disease is prescribed this medication, as close monitoring of liver function tests will be necessary to detect any signs of liver damage early on. It is important to assess and consider the patient's liver condition before initiating valproic acid therapy to prevent potential adverse effects.