ATI RN
Pediatric Genetic Questions
Question 1 of 5
Male breast cancer is associated with mutations in:
Correct Answer: B
Rationale: BRCA2 mutations increase male breast cancer risk more than BRCA1.
Question 2 of 5
The presence of two or more cell lines from different zygotes in a single individual is known as:
Correct Answer: D
Rationale: Chimaerism is two or more cell lines from different zygotes (e.g., fused embryos); mosaicism is from one zygote.
Question 3 of 5
Which of the following disorders does not show X-linked inheritance?
Correct Answer: B
Rationale: Tay-Sachs is autosomal recessive; others are X-linked.
Question 4 of 5
Repeat core sequences consisting of 2,3, or 4 base pairs are known as what?
Correct Answer: B
Rationale: Microsatellites are short tandem repeats of 2-4 base pairs.
Question 5 of 5
Which of the following diagnostic techniques is of no value for the diagnosis of neural tube defects?
Correct Answer: B
Rationale: CVS tests chromosomes, not neural tube defects (NTDs); others detect NTDs via AFP or imaging.