ATI RN
Pediatric Immunization Practice Questions Questions
Question 1 of 5
Makes integrins more 'sticky'
Correct Answer: D
Rationale: Chemokines activate integrins to enhance adhesion.
Question 2 of 5
Natural killer cells are thought to fill the gap between initial innate response and adaptive immune response. They evolved to detect low levels of MHC caused by the diseases of and
Correct Answer: C
Rationale: NK cells detect reduced MHC class I expression, common in herpes virus infections and tumor cells, bridging innate and adaptive immunity.
Question 3 of 5
Subunit vaccines contains components from pathogens, which are inactivated and referred to as These vaccines are generally of low immunogenicity and may need to work effectively.
Correct Answer: D
Rationale: Subunit vaccines use toxoids or antigens and require adjuvants to boost immunogenicity.
Question 4 of 5
A patient in their early 20s presents with recurrent bacterial infections. Lab work shows B cells in the periphery as well as low immunoglobulin levels. History shows immunoglobulin levels have decreased with age. Which of the following is the most likely?
Correct Answer: D
Rationale: Common variable immunodeficiency (CVID) presents with low immunoglobulin levels and recurrent infections, often manifesting in young adults.
Question 5 of 5
A patient presents for a follow-up visit after a diagnosis of systemic lupus erythematosus (SLE). The physician suspects a misdiagnosis after finding immune complexes accumulated in the blood, lymph, and tissues. Which of the following is the most likely?
Correct Answer: C
Rationale: Early complement deficiencies (e.g., C1, C2, C4) lead to immune complex accumulation, mimicking SLE.