Major risk factors for recurrence of febrile seizure include

Correct Answer: D

Rationale: Major risk factors for febrile seizure recurrence include complex seizurprolonged, focal, or multiple due to their strong recurrence link (~50%). Lower fever , family history of seizuror epilepsy , and low sodium are minor risks with weaker impact. Complex seizurseverity marks D as the correct answer.

Correct Answer: A

Rationale: Higher relapse risk after AED withdrawal includlonger epilepsy duration , multiple seizure typ, polytherapy , and abnormal EEG , reflecting disease severity. Younger onset is not a consistent risk; older onset may signal worse prognosis. This counterintuitive finding makes A the exception and correct answer.

Correct Answer: C

Rationale: Nonketotic hyperglycinemia presents with hiccups, seizures, and coma from glycine accumulation disrupting neurotransmission. Propionic acidemia and maple syrup urine disease cause acidosis and odor, not hiccups. Leigh and adrenoleukodystrophy are later-onset. Glycinunique signs make C the correct answer.

Correct Answer: A

Rationale: Midazolam has the strongest evidence for refractory status epilepticus, per trials (e.g., RAMPART), due to rapid onset and efficacy via IM/IV routes. Propofol , levetiracetam , phenytoin , and phenobarbital are options, but midazolams data superiority makes A the correct answer.

Correct Answer: B

Rationale: Café-au-lait maculoccur in NF-1, Noonan , Fanconi , Gaucher , and Hurler syndromes, tied to genetic or metabolic defects. Ataxia telangiectasia featurtelangiectasia, not macules. This phenotypic distinction make B the exception and correct answer.