Major depression is characterized by

Correct Answer: D

Rationale: Major depression includes core symptoms like weight changes, sleep disturbances, and dysphoric mood. All listed options are possible features of the disorder.

Correct Answer: B

Rationale: Aspirin is less commonly associated with drug-induced anaphylaxis compared to penicillin, NSAIDs, radiocontrast media, and vaccines.

Correct Answer: C

Rationale: An increased anion gap metabolic acidosis is caused by acid accumulation, such as in salicylate toxicity, where excess acids like lactate and ketones contribute to the gap.

Correct Answer: C

Rationale: Digitalis (digoxin) is contraindicated in hypertrophic cardiomyopathy as it can increase left ventricular outflow obstruction.

Correct Answer: D

Rationale: Kawasaki disease is diagnosed based on fever for ≥5 days and at least four of five criteria, including bilateral bulbar conjunctival injection without exudate.