ATI RN
Pediatric Immunization NCLEX Questions Questions
Question 1 of 5
Macrophages recognize microorganisms through the Interaction of their substances with what receptor?
Correct Answer: D
Rationale: Macrophages use pattern recognition receptors (PRRs) to detect microbial PAMPs.
Question 2 of 5
A 66-year-old man with advanced pancreatic cancer develops cachexia (loss of mass) Which cytokine is primarily responsible for the cachexia seen in certain patients with cancer or debilitating infections?
Correct Answer: D
Rationale: TNF-α drives cachexia by promoting muscle wasting and metabolic changes in cancer.
Question 3 of 5
A CD3pos cell that secretes perforin and granzyme is a:
Correct Answer: C
Rationale: CD3+ cytotoxic T cells (CD8+) secrete perforin and granzyme to kill target cells.
Question 4 of 5
Which of the following peripheral immune tissues is likely to be different from teen through life to old age?
Correct Answer: C
Rationale: The thymus involutes with age, reducing T cell output.
Question 5 of 5
A 4.5-year-old boy presented with history of recurrent attack of secretary otitis media and purulent nasal discharge, Haemophilus influenza revealed by culture of ear discharge, on physical examination there is no tonsillar tissue and no palpable lymph nodes. Of the following, the MOST appropriate test to confirm the diagnosis is
Correct Answer: D
Rationale: The absence of lymphoid tissue and recurrent infections suggest X-linked agammaglobulinemia. Measuring antibodies to routine immunizations tests B-cell function, confirming the diagnosis.