Lytic life cycle of phages does not include

Correct Answer: A

Rationale: The correct answer is A: germination. In the lytic life cycle of phages, germination is not a stage. The lytic cycle involves adsorption, penetration, replication, assembly, and lysis. Germination is typically associated with the lysogenic cycle, where the phage DNA integrates into the host genome. Therefore, A is the correct answer. Choices B, C, and D are incorrect because they are all stages of the lytic cycle. Penetration refers to the injection of phage DNA into the host cell, adsorption is the attachment of the phage to the host cell, and lysis is the final stage where the host cell bursts, releasing new phages.

Correct Answer: A

Rationale: The correct answer is A: Toxoplasmosis. Toxoplasmosis is a parasitic infection caused by Toxoplasma gondii, which can be transmitted from mother to fetus during pregnancy, leading to congenital toxoplasmosis. This infection can result in stillbirth, multiple developmental defects, and intrauterine death. Leishmaniasis (B), Malaria (C), and Amebiasis (D) are caused by different parasites and do not typically lead to intrauterine death or developmental defects in the fetus.

Correct Answer: D

Rationale: The correct answer is D: Chocolate agar. Neisseria meningitidis is a fastidious organism that requires enriched media for growth. Chocolate agar contains heat-treated blood that provides essential nutrients for the growth of N. meningitidis. The other choices, A: Levine agar, B: Lowenstein-Jensen agar, and C: TCBS agar, do not provide the specific nutrients required for the growth of N. meningitidis. Therefore, only choice D, Chocolate agar, supports the growth of N. meningitidis due to its enriched composition.

Correct Answer: B

Rationale: The correct answer is B: Mycobacterium leprae. This microorganism can only be cultured in the footpads of mice or a species of armadillo due to its specific growth requirements. Mycobacterium tuberculosis (choice A) can be cultured in various culture media in the laboratory. Neisseria gonorrhoeae (choice C) can be cultured on selective media like Thayer-Martin agar. Mycoplasma (choice D) can be cultured in cell cultures or specialized media. Therefore, the unique growth pattern of Mycobacterium leprae makes it the correct answer.

Correct Answer: C

Rationale: The correct answer is C: Method of Moller. This method uses malachite green to stain bacterial spores due to their resistance to decolorization. The other choices, A, B, and D, are incorrect because Romanovski-Gymsa is used for staining blood smears, Ziehl-Nielsen is used for acid-fast bacteria, and Neisser is used for staining Neisseria species, not bacterial spores.

Correct Answer: D

Rationale: The correct answer is D: S phase. During the S phase of the cell cycle, DNA replication takes place to ensure each daughter cell receives a complete set of genetic material. This phase is characterized by the synthesis of new DNA strands. In contrast, choices A, B, and C (G phase, Prophase, Metaphase) are not associated with DNA replication. The G phase is a period of cell growth, Prophase is the initial stage of mitosis, and Metaphase is when chromosomes align. Therefore, the S phase is the specific stage where DNA replication occurs, making it the correct answer.

Correct Answer: A

Rationale: The correct diagnosis is A: Balantidiasis. The presence of large ciliated protozoa with a kidney-shaped macronucleus is characteristic of Balantidium coli, the causative agent of balantidiasis. The ciliated trophozoites of Balantidium coli are unique compared to the other choices. Giardiasis is caused by Giardia lamblia, which has flagella and not cilia. Amoebiasis is caused by Entamoeba histolytica, which lacks cilia. Trichomoniasis is caused by Trichomonas vaginalis, which also lacks cilia. Therefore, based on the specific morphology described, the correct diagnosis is Balantidiasis.

Correct Answer: B

Rationale: The correct answer is B: eukaryotic. Eukaryotic cells have a well-defined nucleus that encloses the genetic material. The nucleus is a distinguishing feature of eukaryotic cells, separating them from prokaryotic cells (choice A) which lack a nucleus. Anucleate cells (choice C) are cells that do not have a nucleus at all. Haploid cells (choice D) contain a single set of chromosomes, but this does not necessarily imply the presence of a nucleus. Therefore, the presence of a nucleus is what categorizes cells as eukaryotic.

Correct Answer: C

Rationale: The correct answer is C: orphan drugs. Orphan drugs are medications developed to treat rare diseases affecting fewer than 200,000 patients. These diseases often lack attention from pharmaceutical companies due to the high cost and limited market potential. Orphan drugs receive special incentives and regulatory support to encourage their development. A: Secondary drugs do not specifically refer to medications for rare diseases. B: Minor drugs is not a recognized term in the context of rare disease medications. D: Specialty drugs typically refer to high-cost medications used to treat complex or chronic conditions, but not necessarily rare diseases.