Lovastatin (Mevacor) plus a bile-acid binding resin causes regression of coronary lesions in about one third of treated patients. This consideration is:

Correct Answer: A

Rationale: The correct answer is A: TRUE. Lovastatin combined with a bile-acid binding resin has been shown to cause regression of coronary lesions in about one third of treated patients. This is supported by clinical studies and research, demonstrating the effectiveness of this combination therapy in improving coronary health. The other choices are incorrect because they do not accurately reflect the evidence and outcomes of this specific treatment approach. Choice B (FALSE) is incorrect because there is evidence to support the regression of coronary lesions with this treatment. Choice C (All) is incorrect because not all patients treated with this combination therapy experience regression of coronary lesions. Choice D (None) is incorrect as there is a significant proportion of patients who do benefit from this treatment in terms of lesion regression.

Correct Answer: D

Rationale: The correct answer is D: Hydrocortisone, as it is a glucocorticoid, not a mineralocorticoid. Mineralocorticoids regulate electrolyte and fluid balance, primarily aldosterone, deoxycorticosterone, and fludrocortisone. Hydrocortisone primarily functions as a glucocorticoid to regulate metabolism and immune response, not electrolyte balance.

Correct Answer: A

Rationale: The correct answer is A: Inhibition of bacterial cell division. Bacteriostatic effect refers to the ability to inhibit the growth and reproduction of bacteria without necessarily killing them. By inhibiting bacterial cell division, it prevents the bacteria from multiplying and causing further infection. This is different from choice B as it specifically targets cell division rather than just growth. Choice C is incorrect as it describes bactericidal effect, which involves destroying bacterial cells. Choice D is unrelated as bacterial L-forms are a specific type of bacterial cell variant, not related to bacteriostatic effect.

Correct Answer: D

Rationale: Resorptive sulfonamides are known to cause hematological adverse effects. Hemolytic anemia occurs due to the destruction of red blood cells, thrombocytopenia is a decrease in platelet count leading to bleeding disorders, and granulocytopenia is a reduction in granulocyte count affecting immunity. Therefore, all of the above choices (A, B, and C) are correct as resorptive sulfonamides can lead to hemolytic anemia, thrombocytopenia, and granulocytopenia. These adverse effects are well-documented in literature and clinical practice.

Correct Answer: A

Rationale: The correct answer is A: Levamisole. Levamisole blocks acetylcholine transmission at the myoneural junction of helminthes by inhibiting cholinesterase enzyme. This leads to paralysis and expulsion of the parasites from the host. Mebendazole (B) works by inhibiting microtubule synthesis in helminthes. Piperazine (C) causes paralysis by hyperpolarizing the helminth's muscle cells. Niclosamide (D) disrupts the helminth's energy metabolism. Therefore, Levamisole is the correct choice for blocking acetylcholine transmission specifically.