ATI RN
ATI Practice Exam Pharmacology The Hematologic System Questions
Question 1 of 5
Louie, who is to receive a blood transfusion asks the nurse what is the most common type of infection he could receive from the transfusion. The nurse teaches him that approximately 1 in 250,000 patients contract:
Correct Answer: B
Rationale: Hepatitis C infection is the most common transfusion-transmitted infection, with an estimated risk of 1 in 250,000 units of blood. While the risk of HIV and hepatitis B has significantly decreased due to improved screening and testing, hepatitis C remains a concern. West Nile virus is rare and region-specific. The nurse should reassure Louie that the blood supply is rigorously tested, but hepatitis C is the most likely infection, albeit still rare.
Question 2 of 5
Age associated changes in pharmacokinetics include:
Correct Answer: A
Rationale: Aging reduces creatinine clearance in about two-thirds of individuals due to declining renal function, a true statement impacting drug excretion. Body fat increases, not decreases, with age, altering distribution of lipophilic drugs, so that's false. Total body water decreases, not increases, affecting hydrophilic drugs. Conjugation (phase II) is less affected than oxidation (phase I) by age, making that false. Absorption isn't significantly altered by age alone. Reduced renal clearance is a critical age-related change, necessitating dose adjustments for renally cleared drugs like digoxin.
Question 3 of 5
A client has been using sildenafil (Viagra) for several months. Which client reports would the nurse interpret as an adverse effect of this medication?
Correct Answer: A
Rationale: Sildenafil (Viagra) commonly causes nasal congestion due to vasodilation affecting nasal blood vessels, a frequent adverse effect tied to its mechanism. Earache isn't a recognized side effect-sildenafil targets vascular smooth muscle, not auditory systems. Blurry vision occurs from PDE-6 inhibition in the retina, another known issue. Priapism, a sustained erection, is a rare but serious risk requiring urgent care. Nasal congestion stands out as a typical, manageable effect, reflecting sildenafil's systemic vasodilatory impact, distinct from less common visual or emergent issues, and aligns with patient reports needing monitoring.
Question 4 of 5
Following ingestion, a drug crosses a membrane from an area of higher concentration to an area of lower concentration. This is an example of
Correct Answer: C
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 5 of 5
The patient has been treated by the same physician for 2 years and has had insomnia the entire time. Many different medications have been tried with limited success. What should be the nurse's primary assessment at this time?
Correct Answer: A
Rationale: Persistent insomnia despite meds suggests a primary disorder like sleep apnea-e.g., obstructed breathing disrupts sleep-needing assessment (e.g., EEG), not just med failure. Selling meds lacks evidence. Addiction or personality disorders don't explain resistance. Sleep apnea fits chronicity, per sleep science.