ATI RN
Quizlet Pharmacology ATI Questions
Question 1 of 5
Lorazepam can be safely used as a preanesthetic medication in a patient undergoing liver transplantation without fear of excessive CNS depression because the drug is
Correct Answer: C
Rationale: Lorazepam is a benzodiazepine commonly used as a preanesthetic medication due to its anxiolytic and sedative properties. In patients undergoing liver transplantation, where hepatic function is compromised, drugs that rely on liver metabolism could accumulate and cause excessive central nervous system depression. Lorazepam's key advantage lies in its pharmacokinetic profile: it undergoes glucuronidation, a conjugation process that occurs outside the liver, primarily in the kidneys. This extrahepatic metabolism ensures that its clearance is less affected by liver dysfunction, reducing the risk of prolonged or excessive sedation. Unlike other benzodiazepines that depend heavily on hepatic cytochrome P450 enzymes, lorazepam's metabolism is more predictable in such patients, making it a safer choice. Excretion in unchanged form or secretion into the GI tract does not apply, and while it is anxiolytic, it does have CNS depressant effects, ruling out other options. Naloxone reverses opioids, not benzodiazepines.
Question 2 of 5
The client is prescribed a nasal decongestant spray. What information should the nurse include when educating the client about how to use this medication?
Correct Answer: D
Rationale: Nasal decongestant sprays (e.g., oxymetazoline) risk rebound congestion if used beyond 3-5 days, and excess drainage into the mouth should be spat out to avoid systemic effects (correct answers: 1, 3, 5). Blowing the nose clears passages, and limiting use prevents rebound, both key. Water isn't relevant. Choice D ensures safe administration, minimizing ingestion risks.
Question 3 of 5
A patient has been changed from a first generation H1 receptor antagonist to a second generation H1 receptor antagonist. The nurse evaluates that the patient understands the benefit of this change when which statement is made?
Correct Answer: D
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 4 of 5
A client is prescribed propranolol (Inderal) for migraines. Which statement by the client indicates a need for further teaching?
Correct Answer: B
Rationale: Propranolol, a beta-blocker, prevents migraines but requires consistent use'stopping if migraines cease risks rebound, showing a teaching gap. Pulse checking monitors bradycardia. Tiredness and orthostasis are expected. Abrupt cessation can worsen migraines, critical in prophylaxis where steady-state matters, making B the statement needing correction.
Question 5 of 5
The following drugs are absorbed predominantly through active transport systems:
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.