ATI RN
Pediatric Immunity NCLEX Questions Questions
Question 1 of 5
Long-term effective therapy for the patient described in Question 2 is best accomplished with
Correct Answer: B
Rationale: Interferon-γ is a standard long-term therapy for chronic granulomatous disease (CGD) as it enhances phagocyte function and reduces infection frequency. IVIG is used for antibody deficiencies, IL-2 for T-cell issues, and bone marrow transplantation for severe combined immunodeficiencies, not primarily for CGD.
Question 2 of 5
Which of the following tests is an effective screening for T-cell function?
Correct Answer: A
Rationale: Absolute lymphocyte count is a simple, effective screening test for T-cell function, as T cells constitute most lymphocytes. Low counts suggest T-cell deficiency.
Question 3 of 5
Delayed separation of the umbilical cord after birth suggests which type of immune dysfunction?
Correct Answer: D
Rationale: Delayed umbilical cord separation is a hallmark of phagocyte defects, particularly leukocyte adhesion deficiency (LAD), due to impaired neutrophil migration.
Question 4 of 5
Delayed separation of umbilical cord, absence of pus at site (s) of infection, and poor wound healing suggest
Correct Answer: D
Rationale: Neutrophil defects, such as leukocyte adhesion deficiency, impair pus formation and wound healing due to ineffective neutrophil migration.
Question 5 of 5
Pancreatic insufficiency, metaphyseal chondrodysplasia, autosomal recessive inheritance, defective chemotaxis, and neutropenia are features of
Correct Answer: D
Rationale: Shwachman-Diamond syndrome includes pancreatic insufficiency, skeletal abnormalities, and neutropenia with defective chemotaxis.