ATI RN
Pharmacology ATI Test Bank Questions
Question 1 of 5
Local anaesthetic agents:
Correct Answer: D
Rationale: Local anesthetics (e.g., lidocaine) block sodium channels, not potassium, halting depolarization, so that's false. They prevent depolarization, not repolarization, making that false. Vasoconstrictors (e.g., epinephrine) prolong action, not vasodilators, which shorten it, so that's incorrect. High extracellular potassium enhances activity by depolarizing membranes closer to threshold, a true statement. High calcium reduces efficacy by stabilizing membranes. The potassium effect is a subtle but real modulator of anesthetic potency, relevant in tissue conditions.
Question 2 of 5
Amoxicillin is prescribed for a patient who has a respiratory infection. The nurse is teaching the patient about this medication and realizes that more teaching is needed when the patient makes which statement?
Correct Answer: A
Rationale: Amoxicillin is an antibiotic that is generally well-absorbed with or without food, but taking it with food can help reduce gastrointestinal side effects such as nausea. The statement 'This medication should not be taken with food' indicates a misunderstanding, as food does not significantly impair its absorption. The other statements are correct: completing the prescription prevents antibiotic resistance, reporting genital itching is important for identifying potential yeast infections, and excess bleeding could indicate a rare but serious side effect like thrombocytopenia.
Question 3 of 5
A 33-year-old man spends the morning outside gardening in the sun on a warm spring day. He develops a tension headache, and the only medication he has at home is aspirin. After taking two regular-sized aspirin tablets, there was an increase in his respiration rate. What is the reason for the increased respirations?
Correct Answer: B
Rationale: Aspirin (salicylates) at standard doses (two tablets) can cause respiratory changes. Option , CO2 receptor agonism, is incorrect-salicylates don't target carotid bodies directly. Option , direct stimulation of the respiratory center, is correct-salicylates stimulate the medullary respiratory center, increasing respiration rate, a known early effect in salicylate toxicity. Option , shifting the oxygen dissociation curve, is unrelated to aspirin's action. Option , uncoupling oxidative phosphorylation, occurs in overdose, causing metabolic acidosis and compensatory hyperventilation, but not at this dose. Here, the mild increase in respiration aligns with central stimulation, not severe metabolic disruption. This reflects aspirin's pharmacological effect on brainstem respiratory control, distinct from overdose scenarios, explaining the observed hyperventilation in this otherwise healthy man.
Question 4 of 5
What is the therapeutic use for Lithium?
Correct Answer: B
Rationale: Lithium is commonly used as a mood stabilizer in the treatment of bipolar disorder. It is particularly effective in reducing the frequency and severity of manic episodes. By stabilizing mood and decreasing manic symptoms, lithium helps to prevent the occurrence of acute manic episodes in individuals with bipolar disorder. It does not specifically target blood pressure, seizure activity, or urinary output.
Question 5 of 5
The nurse administers a vaccine to a child. What is the best understanding of the nurse as it relates to the manufacture of this vaccine?
Correct Answer: B
Rationale: Vaccines are typically produced using animal cells (e.g., eggs) or microorganisms (e.g., bacteria, yeast) to grow antigens, mimicking natural pathogen processes for immunity. Plant extracts aren't standard-most use biological systems. Combination products are rare; animal/microbial methods dominate. Lab synthesis applies to small molecules, not complex vaccines. This understanding reflects standard bioprocessing, ensuring effective immune response.