ATI RN
Pediatric Infectious Disease Questions
Question 1 of 5
Leukocoria is a manifestation of
Correct Answer: B
Rationale: Leukocoria (white pupil) is a classic sign of retinoblastoma.
Question 2 of 5
Almost all the following pediatric malignancies require chemotherapy EXCEPT
Correct Answer: B
Rationale: Low-grade neuroblastoma may be managed with observation or surgery alone in some cases, unlike the others requiring chemotherapy.
Question 3 of 5
A translocation between chromosomes 9 and 22 (BCR-ABL) plays an important role in the development of
Correct Answer: B
Rationale: The BCR-ABL translocation (Philadelphia chromosome) is a hallmark of chronic myeloid leukemia.
Question 4 of 5
The MOST common chromosomal translocation in pediatric acute lymphoblastic leukemia is
Correct Answer: A
Rationale: t(12;21) (TEL-AML1) is the most common translocation in pediatric ALL, occurring in about 25% of cases.
Question 5 of 5
A boy with acute lymphoblastic leukemia is assigned to be of high risk group if he had got which of the following features?
Correct Answer: B
Rationale: Testicular involvement at diagnosis indicates high-risk ALL due to extramedullary spread.