Jacob, a 33-year-old construction worker, complains of a "lump on his back" over his scapula. It has been there for about a year and is getting larger. He says his wife has been able to squeeze out a cheesy-textured substance on occasion. He worries this may be cancer. When gently pinched from the side, a prominent dimple forms in the middle of the mass. What is most likely?

Correct Answer: B

Rationale: The correct answer is B: A sebaceous cyst. A sebaceous cyst typically presents as a lump underneath the skin that can be squeezed to release a cheesy substance, consistent with Jacob's description. The formation of a prominent dimple when gently pinched is characteristic of a cyst, indicating it is filled with fluid or semi-solid material. Sebaceous cysts are usually benign and can grow slowly over time. Incorrect choices: A: An enlarged lymph node - Unlikely as lymph nodes are typically not associated with cheesy discharge or the formation of a dimple when pinched. C: An actinic keratosis - Unlikely as actinic keratosis is a precancerous skin condition caused by sun exposure, not presenting with cheesy discharge or a dimple. D: A malignant lesion - Unlikely as malignant lesions usually do not produce cheesy discharge and are more aggressive in growth compared to a sebaceous cyst.

Correct Answer: B

Rationale: The correct answer is B: 3+. Bounding pulses indicate a 3+ strength on a scale of 0 to 3. This reflects increased blood flow or pressure in the arteries, which can be a sign of conditions like peripheral vascular disease. A strength of 0 indicates no palpable pulse, 1+ is weak and thready, 2+ is normal, and 3+ is bounding. In this case, the patient's history of coronary artery disease and diabetes may contribute to the increased blood flow, leading to bounding pulses. Choices A, C, and D are incorrect as they do not accurately reflect the strength of the pulses based on the given assessment findings.

Correct Answer: B

Rationale: The correct answer is B: It was the first device to produce X-rays. The Crookes tube, invented by William Crookes, was crucial in the development of modern imaging technologies because it was the first device to produce X-rays. X-rays revolutionized medical diagnostics and imaging, leading to significant advancements in healthcare. Choices A, C, and D are incorrect because the primary significance of the Crookes tube was its role in producing X-rays, not demonstrating electromagnetic radiation principles, paving the way for the electron microscope, or advancements in nuclear medicine.

Correct Answer: D

Rationale: The correct answer is D: Repeat PSA in 6 months. In this case, the patient's PSA levels have decreased from 12 ng/mL to 10 ng/mL after treatment with tamsulosin and removal of the Foley catheter. Given the improvement in PSA levels, it is reasonable to monitor for further changes before considering invasive procedures like transrectal ultrasound and biopsy (choice A), which may not be necessary at this time. Empiric finasteride (choice B) is not indicated as the patient is already responding well to tamsulosin. A bone scan (choice C) is not necessary at this stage as there are no indications of metastasis. Therefore, repeating the PSA in 6 months allows for continued monitoring of the patient's prostate health without subjecting him to unnecessary procedures.

Correct Answer: B

Rationale: The correct answer is B: Potential congenital deformity. This observation suggests a condition called "low-set ears," which can be a sign of certain congenital anomalies affecting the development of the head and neck structures during fetal growth. It is important to investigate further to rule out any associated syndromes or genetic disorders. Choice A: Normal anatomical variation is incorrect because this positioning is not commonly considered a normal variation in the general population. Choice C: Increased risk of hearing loss is incorrect as the position of the ears alone does not directly correlate with hearing loss. Choice D: No clinical significance is incorrect because this observation warrants further evaluation to assess for potential underlying issues.

Correct Answer: D

Rationale: The correct answer is D: Dry and rough. In hypothyroidism, there is reduced secretion of sweat and oils, leading to dry skin. The lack of hydration causes the skin to become rough. This correlates with the clinical presentation of fatigue, weight gain, and hair loss, which are common symptoms of hypothyroidism. Choices A and B are incorrect because moisture is reduced in hypothyroidism, resulting in dry skin. Choice C is incorrect because the lack of oils in hypothyroidism leads to rough skin texture, not smooth.

Correct Answer: D

Rationale: The correct answer is D: It can protect against anogenital lesions. The HPV vaccine can protect against several types of HPV that are known to cause anogenital warts and lesions. This is based on scientific evidence from clinical trials. A: Ideally it should be administered within 3 years of first intercourse - This statement is not accurate. The HPV vaccine is recommended for both males and females between the ages of 9 and 26, regardless of sexual activity. B: It covers against almost every HPV type - This statement is incorrect. While the HPV vaccine covers the most common high-risk HPV types that cause cervical cancer, it does not cover against every HPV type. C: It can be used as adjuvant therapy in cervical cancer - This statement is incorrect. The HPV vaccine is primarily used as a preventive measure to reduce the risk of HPV infection and related health issues, not as a treatment for existing cervical cancer.

Correct Answer: C

Rationale: The correct answer is C: Voluntary stopping of eating and drinking. This is legal throughout the United States because it is considered a patient's right to refuse food and water, even if it may lead to death. This decision is based on the principle of patient autonomy and respects the patient's wishes. Euthanasia (A) involves actively causing death, which is illegal in the United States. Palliative sedation (B) is providing medication to relieve suffering, but not with the intention of hastening death. Physician-assisted death (D) involves a physician providing medication for a patient to self-administer to end their life, which is not legal in all states.

Correct Answer: B

Rationale: The correct answer is B: Migraines with aura. Estrogen in contraceptives can increase the risk of stroke in patients with migraines with aura due to its effect on blood clotting. Estrogen-progestin contraceptives should be avoided in these patients to reduce the risk of adverse cardiovascular events. Choices A, C, and D do not have a direct contraindication to estrogen-progestin contraceptives based on current guidelines.