ATI RN
Foundations in Microbiology Test Bank Questions
Question 1 of 5
It is planned to use the territory of an old cattle burial ground (which is not used for more than 50 years) for building houses. But ground analysis revealed presence of the pathogen of the very dangerous illness. Which of the indicated microorgonisms is likely to remain in the ground for such a long time?
Correct Answer: C
Rationale: Rationale: 1. Bacillus anthracis is a spore-forming bacterium that can survive for decades in the soil. 2. The spores are resistant to harsh conditions and can remain dormant for long periods. 3. This resilience allows Bacillus anthracis to persist in the old cattle burial ground for over 50 years. 4. Mycobacterium bovis, Brucella abortus, and Francisella tularensis are not known for long-term survival in soil. Summary: - Mycobacterium bovis, Brucella abortus, and Francisella tularensis do not have the spore-forming ability. - Mycobacterium bovis causes tuberculosis in cattle. - Brucella abortus causes brucellosis in cattle. - Francisella tularensis causes tularemia in animals and humans.
Question 2 of 5
A 6-year-old boy is brought to the pediatrician by his mother, who complains of low-grade fever, chronic cough and night sweats in her child. She describes the cough as productive, producing white sputum that is sometimes streaked with blood. She also says that her son has lost some weight in the last month. His vital signs include blood pressure of 115/75 mm Hg, heart rate of 110/min., respiratory rate of 18/min. and temperature of 36,6°C. On physical examination, the patient is ill looking. Pulmonary auscultation reveals some fine crackles in the right upper lobe. The pediatrician suspects an active infection and performs Mantoux test. Intradermal injection of which of the following substances has been most likely used by pediatrician for screening test in this clinical case?
Correct Answer: A
Rationale: The correct answer is A: Tuberculin. In this clinical scenario, the patient presents with symptoms suggestive of tuberculosis, including chronic cough, night sweats, weight loss, and hemoptysis. The Mantoux test, also known as the tuberculin skin test, is used to screen for tuberculosis. Tuberculin, a purified protein derivative (PPD) derived from Mycobacterium tuberculosis, is injected intradermally. The test elicits a delayed-type hypersensitivity reaction in individuals who have been exposed to the organism in the past. A positive Mantoux test indicates exposure to tuberculosis and does not differentiate between active infection and prior exposure. Explanation for other choices: B: Measles - Measles is a viral infection that presents with a characteristic rash and fever, not consistent with the symptoms described in the case. C: Tetanus and diphtheria toxoids vaccine (Td) - Td vaccine is not used for tuberculosis screening and does not elicit
Question 3 of 5
Disinfection with chemicals acting on cell surface:
Correct Answer: B
Rationale: The correct answer is B: Phenols. Phenols act on the cell surface by disrupting cell membranes and denaturing proteins, leading to cell death. Soaps (A) work by lifting dirt and microbes off surfaces, not directly acting on cell surfaces. Amines (C) are typically used as disinfectants targeting specific enzymes in microbes, not cell surfaces. Polymyxin (D) is an antibiotic that works by disrupting cell membranes internally, not on the cell surface.
Question 4 of 5
A 60-year-old patient was hospitalized to the surgical department because of infection caused by blue pus bacillus (Pseudomonas aeruginosa) which is sensative to penicillin antibiotics. Indicate which of the given penicillins has marked activity to the Pseudomonas aeruginosa?
Correct Answer: A
Rationale: The correct answer is A: Carbenicillin disodium. Carbenicillin is a semisynthetic penicillin that has marked activity against Pseudomonas aeruginosa. This is due to its extended spectrum of activity and increased stability against beta-lactamases produced by Pseudomonas aeruginosa. Carbenicillin is commonly used to treat infections caused by this bacterium. Choice B: Benzylpenicillin (Penicillin G) has limited activity against Pseudomonas aeruginosa. Choice C: Methicillin is not effective against Pseudomonas aeruginosa. Choice D: Oxacillin also has limited activity against Pseudomonas aeruginosa. In summary, Carbenicillin is the correct choice due to its marked activity against Pseudomonas aeruginosa compared to the other penicillins listed.
Question 5 of 5
The enzyme used by bacteria to break down hydrogen peroxide is:
Correct Answer: B
Rationale: The correct answer is B: Catalase. Catalase is the enzyme responsible for breaking down hydrogen peroxide into water and oxygen. This process helps protect the bacteria from oxidative damage caused by hydrogen peroxide. Amylase (A), Lipase (C), and Protease (D) are enzymes that are not involved in breaking down hydrogen peroxide. Amylase is involved in breaking down starch, Lipase breaks down lipids, and Protease breaks down proteins. Therefore, they are not the correct enzymes for the given question.