ATI RN
ATI Pharmacology Study Guide PDF Questions
Question 1 of 5
_____________ is the period of time required for concentration of a drug to be reduced by 50%.
Correct Answer: C
Rationale: Half-life is the period of time required for the concentration of a drug in the body to be reduced by 50%. It is an important pharmacokinetic parameter that helps determine dosing intervals and drug accumulation or clearance. Understanding a drug's half-life is crucial in optimizing dosing regimens and achieving desired therapeutic outcomes. Efficacy refers to the maximum therapeutic effect that a drug can produce. Steady-state concentration is the consistent level of drug concentration achieved after repeated doses. Clearance is the rate at which a drug is removed from the body.
Question 2 of 5
Glyceryl trinitrate for angina is most effective when given:
Correct Answer: C
Rationale: Glyceryl trinitrate, also known as nitroglycerin, is a medication commonly used for the management of angina (chest pain). When administered sublingually (under the tongue), glyceryl trinitrate is rapidly absorbed through the highly vascular sublingual mucosa, leading to a quick onset of action. The sublingual route allows for the drug to enter the bloodstream directly without being metabolized by the liver first, resulting in faster relief of angina symptoms. This makes sublingual administration the most effective route for managing acute episodes of angina. Other routes of administration, such as oral, subcutaneous, intravenous, or intramuscular, would not provide the same rapid and reliable relief for angina.
Question 3 of 5
A patient is beginning isoniazid and rifampin treatment for tuberculosis. The nurse gives the patient which instruction?
Correct Answer: A
Rationale: Adherence to the prescribed regimen is critical in tuberculosis treatment to prevent resistance and ensure efficacy. Skipping doses can lead to treatment failure and drug-resistant TB. Isoniazid and rifampin are typically taken once daily, not three times daily. Antacids can interfere with the absorption of these drugs and should be avoided. There is no specific requirement to take rifampin initially; both drugs should be taken as prescribed.
Question 4 of 5
A 31-year-old male patient has been prescribed propranolol to reduce and prevent angina. What will the nurse assess this patient for related to the medication? (Select all that apply.)
Correct Answer: B
Rationale: Adverse effects of propranolol that the nurse would assess for include allergic reaction, bradycardia, heart failure, cardiac arrhythmias, cerebrovascular accident, pulmonary edema, gastric pain, flatulence, impotence, decreased exercise tolerance, and bronchospasm. The nurse should monitor for these adverse effects and intervene as needed to ensure patient safety.
Question 5 of 5
A patient is about to receive a morning dose of digoxin and has an apical pulse of 53 beats/minute. Which of the following actions should the nurse do first?
Correct Answer: A
Rationale: Digoxin should be withheld if the apical pulse is below 60 beats/minute in adults, as it can exacerbate bradycardia and lead to serious cardiac complications. The nurse should hold the dose and notify the healthcare provider for further instructions. Administering the dose (B) or contacting the charge nurse (C) without holding the dose is inappropriate.