Ipratropium is a synthetic bronchodilator atropine substitute administered by:

Correct Answer: D

Rationale: The correct answer is D: Inhalation. Ipratropium is a bronchodilator used to treat conditions like asthma and chronic obstructive pulmonary disease (COPD). Inhalation allows direct delivery to the lungs, where it acts locally to relax the smooth muscle and dilate the airways, providing rapid relief of bronchospasm. Oral route (A) would result in poor absorption and systemic side effects. Intravenous (B) and subcutaneous (C) injections are not preferred due to the risk of systemic effects and lack of targeted action. Thus, inhalation is the most effective and appropriate route for ipratropium administration.

Correct Answer: D

Rationale: The correct answer is D, Edrophonium, because it is not a parasympatholytic drug but rather a parasympathomimetic drug used for diagnosing myasthenia gravis. Atropine (A), Propantheline (B), and Pirenzepine (C) are all parasympatholytic drugs that inhibit the parasympathetic nervous system by blocking acetylcholine receptors. Atropine is a nonselective muscarinic receptor antagonist, Propantheline is an antimuscarinic drug used to treat gastrointestinal disorders, and Pirenzepine is a selective M1 receptor antagonist used to reduce gastric acid secretion. Therefore, D is the correct choice as it does not belong to the category of parasympatholytic drugs.

Correct Answer: D

Rationale: The correct answer is D: Haloperidol. Haloperidol is a dopamine receptor antagonist, which means it blocks dopamine receptors. Dopamine induces renal vasodilation by acting on dopamine receptors in the kidneys. Therefore, blocking these receptors with haloperidol would antagonize the renal vasodilation effect of dopamine. A: Propranolol is a beta-blocker that acts on beta receptors, not dopamine receptors. B: Atropine is a muscarinic antagonist and does not affect dopamine receptors. C: Prazosin is an alpha-1 adrenergic antagonist and does not target dopamine receptors.

Correct Answer: A

Rationale: Neostigmine is the correct choice for treating myasthenia gravis as it is an acetylcholinesterase inhibitor that increases acetylcholine levels, improving muscle strength. Pilocarpine is a muscarinic agonist used for glaucoma. Succinylcholine is a depolarizing neuromuscular blocker used for intubation. Tubocurarine is a non-depolarizing neuromuscular blocker.

Correct Answer: D

Rationale: Adrenaline is a sympathomimetic drug that acts on adrenergic receptors. In acute situations like allergic reactions, bronchial asthma, and heart block, adrenaline can be beneficial due to its bronchodilator and vasoconstrictor effects. However, in angina pectoris, which is caused by reduced blood flow to the heart muscle, the vasoconstrictor effect of adrenaline can worsen the condition by increasing the workload of the heart. Therefore, adrenaline should not be used in angina pectoris.