Involved in allergic responses

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Pediatric Immunizations NCLEX Questions Questions

Question 1 of 5

Involved in allergic responses

Correct Answer: B

Rationale: IgE is key in allergic responses, binding to mast cells and basophils to trigger histamine release.

Question 2 of 5

Which of the following is used extensively to detect antigens in cells or tissue sections, as well as to screen for auto-antibodies to cell or tissue antigens?

Correct Answer: B

Rationale: Fluorescent antibodies are extensively used in immunofluorescence to detect antigens in cells or tissues.

Question 3 of 5

is frequently found on the surface of B cells co-expressed with These two classes are co-expressed not by class switching but by alternative processing of a primary RNA transcript. Both molecules expressed on the single mature B cell have the same binding specificity for antigen.

Correct Answer: B

Rationale: IgD and IgM are co-expressed on mature B cells via alternative RNA processing, sharing antigen specificity.

Question 4 of 5

Which of the following are located in chromosome 7 within human T-cell receptors?

Correct Answer: C

Rationale: The gamma (γ)-locus is located on chromosome 7, along with the alpha (α)-locus.

Question 5 of 5

The TCR binds with , and the relatively surface of the TCR interacts with its ligand.

Correct Answer: D

Rationale: The TCR binds both MHC and peptide antigen with a flat surface for recognition.

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