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free microbiology test bank questions pdf Questions
Question 1 of 9
Infectious agents of various ultrastructures can be etiological agents of infectious diseases. Which of the groups named below HAS NO cellular structure, protein synthesizing, enzyme and energy systems?
Correct Answer: A
Rationale: The correct answer is A: Viruses. Viruses are acellular, meaning they lack cellular structure, protein synthesizing ability, enzymes, and energy systems. They are essentially genetic material (DNA or RNA) enclosed in a protein coat. Fungi (B), bacteria (C), and protozoa (D) are all cellular organisms with protein synthesizing, enzyme, and energy systems. Viruses rely on host cells to replicate and carry out metabolic functions, making them distinct from other groups.
Question 2 of 9
Which of the following media is used to isolate Neisseria gonorrhoeae?
Correct Answer: B
Rationale: The correct answer is B: Thayer-Martin agar. This selective media contains antibiotics that inhibit the growth of other organisms while allowing Neisseria gonorrhoeae to grow. The antibiotics in Thayer-Martin agar include vancomycin, colistin, nystatin, and trimethoprim, which target different types of bacteria, ensuring the isolation of N. gonorrhoeae. Phenylethyl alcohol agar (A) is used to isolate gram-positive organisms, not N. gonorrhoeae. MacConkey agar (C) is selective for gram-negative enteric bacteria. Mannitol salt agar (D) is used for isolating Staphylococcus species based on their ability to ferment mannitol.
Question 3 of 9
Which bacteria produce exotoxins that affect the nervous system?
Correct Answer: A
Rationale: The correct answer is A: Clostridium botulinum and Clostridium tetani. Both bacteria produce exotoxins that affect the nervous system. Clostridium botulinum produces botulinum toxin, causing botulism, leading to muscle paralysis. Clostridium tetani produces tetanospasmin, causing tetanus, leading to muscle stiffness and spasms. Choice B (Escherichia coli and Salmonella) are known for causing gastrointestinal infections, not specifically affecting the nervous system. Choice C (Bacillus anthracis and Listeria monocytogenes) produce toxins that primarily affect other body systems, not the nervous system. Choice D (Pseudomonas aeruginosa and Staphylococcus aureus) are associated with skin and respiratory infections, not neurological effects.
Question 4 of 9
The so-called “red tide†is generally caused by which of the following organisms?
Correct Answer: D
Rationale: The correct answer is D: Dinoflagellates. Red tides are caused by the rapid growth of certain species of dinoflagellates, which are single-celled algae. These algae produce toxins that can harm marine life and humans. Lichens (A) are not associated with red tides. While some bacteria (B) can contribute to harmful algal blooms, they are not the primary cause of red tides. Pfiesteria (C) is a type of harmful algal species, but it is not the main organism responsible for red tides. Therefore, the correct answer is dinoflagellates (D) due to their ability to cause red tides through toxin production.
Question 5 of 9
A lot of pyoinflammatory processes in oral cavity are caused by anaerobes. What nutrient medium can be used for control of wound textile contamination by anaerobes?
Correct Answer: A
Rationale: The correct answer is A: Kitt-Tarozzi. This medium contains blood and hemin, which are essential nutrients for the growth of anaerobes. Blood provides a source of iron, while hemin stimulates the growth of anaerobes. This combination creates an environment conducive for the isolation and identification of anaerobic organisms. B: Endo and C: Roux are selective media primarily used for the isolation of gram-negative bacteria and not specifically designed for anaerobes. D: Sabouraud's is a medium used for the cultivation of fungi, not anaerobes. In summary, Kitt-Tarozzi is the correct choice due to its specific nutrient composition that supports the growth of anaerobes, unlike the other options which are not suitable for this purpose.
Question 6 of 9
Which of the following bacteria is capable of forming spores to survive in extreme conditions?
Correct Answer: B
Rationale: The correct answer is B: Clostridium botulinum. This bacterium is capable of forming spores as a survival mechanism in harsh conditions. Spore formation allows it to remain dormant until conditions become favorable for growth again. Staphylococcus aureus (A), Escherichia coli (C), and Neisseria gonorrhoeae (D) do not form spores and rely on other mechanisms for survival. Staphylococcus aureus is a common skin bacterium, Escherichia coli is a gut bacterium, and Neisseria gonorrhoeae is a sexually transmitted bacterium.
Question 7 of 9
In order to prevent wound infection associated with surgical procedures a patient was given a synthetic antiprotozoan drug with a high activity against Helicobacter pylori. Specify this drug:
Correct Answer: A
Rationale: The correct answer is A: Metronidazole. Metronidazole is a synthetic antiprotozoan drug with high activity against Helicobacter pylori, a bacterium that can cause wound infections. Metronidazole specifically targets anaerobic bacteria like H. pylori, making it effective in preventing wound infections. Incorrect choices: B: Doxycycline hydrochloride - Doxycycline is primarily used for bacterial infections, not protozoan infections like H. pylori. C: Chingamin - Chingamin is not a commonly used drug for treating H. pylori infections or preventing wound infections. D: Acyclovir - Acyclovir is an antiviral drug used to treat herpes infections, not bacterial or protozoan infections like H. pylori.
Question 8 of 9
A patient who has been taking tetracycline for a long time has developed candidosis of mucous membranes. What drug shoul administered for its treatment?
Correct Answer: A
Rationale: The correct answer is A: Itraconazole. Itraconazole is an antifungal medication commonly used to treat candidosis. It works by inhibiting the synthesis of ergosterol, a key component of fungal cell membranes. This action disrupts the integrity of the fungal cell membrane, leading to cell death. Griseofulvin (B) is primarily used to treat fungal infections of the skin and nails, not mucous membranes. Nitrofungin (C) is not commonly used for candidosis treatment. Amphotericin (D) is a potent antifungal medication but is typically reserved for severe or systemic fungal infections due to its potential side effects.
Question 9 of 9
Which of the following proteins are encoded by herpesviruses and required for viral DNA replication?
Correct Answer: A
Rationale: The correct answer is A: viral DNA polymerase. This enzyme is essential for replicating the viral DNA during the herpesvirus life cycle. It catalyzes the synthesis of new DNA strands using the viral genomic template. Ribonucleotide reductase (B) is involved in nucleotide synthesis, but not directly in DNA replication. Neuraminidase (C) is an enzyme found in influenza viruses, not herpesviruses. Thymidine kinase (D) is an enzyme that phosphorylates thymidine, but its role is more related to nucleotide metabolism rather than viral DNA replication.