Infectious agents of various ultrastructures can be etiological agents of infectious diseases. Which of the groups named below HAS NO cellular structure, protein synthesizing, enzyme and energy systems?

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Question 1 of 9

Infectious agents of various ultrastructures can be etiological agents of infectious diseases. Which of the groups named below HAS NO cellular structure, protein synthesizing, enzyme and energy systems?

Correct Answer: A

Rationale: The correct answer is A: Viruses. Viruses are acellular, meaning they lack cellular structure, protein synthesizing ability, enzymes, and energy systems. They are essentially genetic material (DNA or RNA) enclosed in a protein coat. Fungi (B), bacteria (C), and protozoa (D) are all cellular organisms with protein synthesizing, enzyme, and energy systems. Viruses rely on host cells to replicate and carry out metabolic functions, making them distinct from other groups.

Question 2 of 9

Which of the following bacteria is known for causing the disease known as whooping cough?

Correct Answer: A

Rationale: The correct answer is A: Bordetella pertussis. This bacterium is known for causing whooping cough due to its ability to produce toxins that damage the respiratory tract, leading to severe coughing fits. Clostridium tetani causes tetanus, Haemophilus influenzae can cause respiratory infections but not whooping cough, and Staphylococcus aureus is more commonly associated with skin infections. Therefore, A is the correct choice based on its specific association with the disease in question.

Question 3 of 9

After a prolonged isoniazid treatment, the patient developed polyneuritis, paresthesia, memory disorders, and convulsions. What is the most likely mechanism of the described isoniazid side-effects?

Correct Answer: D

Rationale: The correct answer is D. Isoniazid inhibits pyridoxal phosphate synthesis, which is the active form of vitamin B6. Pyridoxal phosphate is essential for various enzymatic reactions, including neurotransmitter synthesis and myelin formation. Therefore, isoniazid-induced pyridoxal phosphate deficiency can lead to neurological symptoms like polyneuritis, paresthesia, memory disorders, and convulsions. A: Disruption of cell membrane synthesis - This is not the mechanism of isoniazid side-effects. B: Inhibition of protein synthesis - Isoniazid does not directly inhibit protein synthesis. C: Inhibition of RNA-synthesis - Isoniazid does not inhibit RNA synthesis; it affects vitamin B6 metabolism.

Question 4 of 9

A patient who has been taking tetracycline for a long time has developed candidosis of mucous membranes. What drug shoul administered for its treatment?

Correct Answer: A

Rationale: The correct answer is A: Itraconazole. Itraconazole is an antifungal medication commonly used to treat candidosis. It works by inhibiting the synthesis of ergosterol, a key component of fungal cell membranes. This action disrupts the integrity of the fungal cell membrane, leading to cell death. Griseofulvin (B) is primarily used to treat fungal infections of the skin and nails, not mucous membranes. Nitrofungin (C) is not commonly used for candidosis treatment. Amphotericin (D) is a potent antifungal medication but is typically reserved for severe or systemic fungal infections due to its potential side effects.

Question 5 of 9

Which bacteria are capable of forming spores that help them survive in extreme conditions?

Correct Answer: C

Rationale: The correct answer is C, both A and B. Clostridium botulinum and Bacillus anthracis are both capable of forming spores, which are a protective mechanism that allows them to survive harsh conditions. Clostridium botulinum causes botulism and forms spores in anaerobic environments, while Bacillus anthracis causes anthrax and forms spores in aerobic environments. Therefore, both choices A and B are correct. Choice D is incorrect as it contradicts the fact that both bacteria are capable of forming spores.

Question 6 of 9

In order to prevent wound infection associated with surgical procedures a patient was given a synthetic antiprotozoan drug with a high activity against Helicobacter pylori. Specify this drug:

Correct Answer: A

Rationale: The correct answer is A: Metronidazole. Metronidazole is a synthetic antiprotozoan drug with high activity against Helicobacter pylori, a bacterium that can cause wound infections. Metronidazole specifically targets anaerobic bacteria like H. pylori, making it effective in preventing wound infections. Incorrect choices: B: Doxycycline hydrochloride - Doxycycline is primarily used for bacterial infections, not protozoan infections like H. pylori. C: Chingamin - Chingamin is not a commonly used drug for treating H. pylori infections or preventing wound infections. D: Acyclovir - Acyclovir is an antiviral drug used to treat herpes infections, not bacterial or protozoan infections like H. pylori.

Question 7 of 9

Which of the following have a fecal oral route of transmission?

Correct Answer: B

Rationale: The correct answer is B: Typhoid fever. Typhoid fever is transmitted through the fecal-oral route, meaning the bacteria from an infected person's feces can contaminate food or water and then be ingested by another person. This can lead to infection and illness. The other choices, diphtheria (A), syphilis (C), and spotted fever (D) are not transmitted through the fecal-oral route. Diphtheria is spread through respiratory droplets, syphilis is primarily sexually transmitted, and spotted fever is transmitted through tick bites. Thus, only Typhoid fever aligns with the fecal-oral route of transmission.

Question 8 of 9

A child with diarrhea had stool microscopy revealing cysts with four nuclei. What is the most likely causative agent?

Correct Answer: A

Rationale: The correct answer is A: Entamoeba histolytica. This pathogen is known to cause amoebic dysentery, characterized by diarrhea with bloody or mucoid stools. The presence of cysts with four nuclei in the stool microscopy is a characteristic feature of Entamoeba histolytica. Other choices are incorrect because Giardia lamblia typically presents with binucleate cysts, Balantidium coli is a ciliated protozoan, and Trichomonas hominis is a non-pathogenic parasite found in the human intestine.

Question 9 of 9

The prokaryotic cell does not possess:

Correct Answer: B

Rationale: The correct answer is B: Endoplasmic reticulum. Prokaryotic cells lack membrane-bound organelles like the endoplasmic reticulum, which is present in eukaryotic cells. Prokaryotes do possess ribosomes for protein synthesis (A), a chromosome (C) for genetic material, and peptidoglycan (D) in their cell walls. The absence of endoplasmic reticulum is a key characteristic that distinguishes prokaryotic cells from eukaryotic cells.

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