Induration along the ventral surface of the penis suggests which of the following?

Correct Answer: C

Rationale: Peyronie's disease is a condition characterized by the formation of fibrous scar tissue in the penis, leading to the development of plaques or indurations along the shaft of the penis, typically on the ventral surface. These plaques can cause penile curvature, pain, and erectile dysfunction. Urethral stricture, testicular carcinoma, and epidermoid cysts are not typically associated with indurations along the ventral surface of the penis.

Correct Answer: A

Rationale: Rheumatoid arthritis is a systemic autoimmune disease that primarily affects the joints. It commonly presents with pain, swelling, and stiffness in multiple small joints such as those in the hands, wrists, and feet. It is more prevalent in females in their 30s to 50s. Rheumatoid arthritis is characterized by chronic inflammation of the synovial membrane, leading to joint damage and deformities over time. Laboratory tests showing elevated inflammatory markers, such as C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR), along with positive rheumatoid factor and anti-cyclic citrullinated peptide (anti-CCP) antibodies, can help in confirming the diagnosis of rheumatoid arthritis.

Correct Answer: D

Rationale: Since the patient, Susanne, has been experiencing headaches, muscle aches, and fatigue for the last 2 months, and a thorough history, examination, and laboratory workup have not revealed a definitive cause, the next step would be to screen for depression. Depression can present with physical symptoms such as headaches, muscle aches, and fatigue. It is important to consider mental health factors that could be contributing to Susanne's symptoms before proceeding with further referrals to specialists. Screening for depression would help in determining if psychological factors are playing a role in her physical symptoms.

Correct Answer: C

Rationale: A "red flag" regarding patients presenting with a headache is their age being over 50. This is because new-onset or persistent headaches in individuals over 50 may raise concerns about underlying serious conditions such as temporal arteritis, brain tumor, or other vascular issues. It is important to thoroughly evaluate and consider these possibilities in older patients with headaches to ensure appropriate management and timely intervention.

Correct Answer: D

Rationale: Finding a bounding carotid pulse suggests a wide pulse pressure, which can be associated with aortic insufficiency. Aortic insufficiency (also known as aortic regurgitation) is characterized by the backflow of blood from the aorta into the left ventricle during diastole due to incomplete closure of the aortic valve. This results in increased stroke volume and left ventricular pressure, leading to widened pulse pressure and a bounding arterial pulse. Therefore, when a bounding carotid pulse is detected in a patient, it is important to search for signs and symptoms of aortic insufficiency, such as a diastolic murmur heard best at the left sternal border and radiating to the neck.

Correct Answer: C

Rationale: The presentation of multiple small, blood-red, raised lesions over the anterior chest and abdomen in a middle-aged man raises concern for a condition known as cherry angiomas. Cherry angiomas are common benign vascular growths often seen in middle-aged and older individuals. They are typically asymptomatic and do not require treatment unless they are bothersome to the patient cosmetically.

Correct Answer: D

Rationale: The correct order of priority for the problem list in this case would be chest pain, headaches, arthritis, and war injury pain. Chest pain should always be a priority as it could indicate a serious or life-threatening condition such as a heart attack. Headaches, while important, are less urgent than chest pain. Arthritis can generally be managed without immediate intervention, making it a lower priority. Finally, the pain from the old war injury, while significant, is not as urgent as the other complaints.

Correct Answer: D

Rationale: Hypertension, or high blood pressure, is not typically associated with causing ulcers in the lower extremities. The most common causes of lower extremity ulcers are arterial insufficiency, venous insufficiency, and diminished sensation in pressure points. Arterial insufficiency leads to decreased blood flow to the lower extremities, causing tissue damage and ulcers. Venous insufficiency results in poor circulation and increased pressure in the veins, leading to ulcers. Diminished sensation in pressure points, often seen in conditions like diabetes, can cause ulcers due to lack of feeling and increased risk of trauma. So, hypertension is not directly related to the development of lower extremity ulcers.

Correct Answer: A

Rationale: The most significant risk factor for breast cancer in the patient's personal and family history is having a first-degree relative with premenopausal breast cancer. This is because the age at which a family member was diagnosed with breast cancer can be indicative of potential genetic predispositions that may increase the patient's own risk of developing the disease. Women with a first-degree relative who was diagnosed with breast cancer before menopause (premenopausal) are at a higher risk themselves compared to those with a family history of postmenopausal breast cancer. In this case, the patient's mother had unilateral breast cancer in her 70s, which suggests a higher risk compared to postmenopausal breast cancer. Other factors such as early age at menarche or age at first live birth are also important in assessing breast cancer risk, but having a first-degree relative with premenopausal breast cancer is the most significant