Indirect action includes all of the following properties EXCEPT:

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Cardiovascular Drug Questions

Question 1 of 5

Indirect action includes all of the following properties EXCEPT:

Correct Answer: C

Rationale: The correct answer is C: Interaction with adrenoreceptors. Indirect action involves affecting catecholamines' release, reuptake, or displacement, not direct interaction with adrenoreceptors. A: Displacement of stored catecholamines is correct as it refers to causing the release of stored catecholamines. B: Inhibition of reuptake is correct as it refers to preventing the reuptake of catecholamines. D: Inhibition of release of endogenous catecholamines is correct as it refers to stopping the release of catecholamines from nerve endings.

Question 2 of 5

Beta-receptor blocking drugs are used in the treatment all of the following diseases EXCEPT:

Correct Answer: C

Rationale: The correct answer is C: Pheochromocytoma. Beta-receptor blocking drugs are contraindicated in pheochromocytoma because they can potentially worsen hypertension due to unopposed alpha-adrenergic effects. Choice A is correct as beta-blockers are commonly used in hypertension, ischemic heart disease, and cardiac arrhythmias. Choice B is incorrect as beta-blockers are used in the treatment of glaucoma to reduce intraocular pressure. Choice D is incorrect as beta-blockers are used to manage symptoms of hyperthyroidism such as tachycardia and tremors.

Question 3 of 5

Which of the following antiseizure drugs produces a voltage-dependent inactivation of sodium channels?

Correct Answer: D

Rationale: The correct answer is D because all of the antiseizure drugs listed (Lamotrigine, Carbamazepin, Phenytoin) produce voltage-dependent inactivation of sodium channels. This mechanism helps to control neuronal excitability and prevent seizure activity. Lamotrigine inhibits voltage-gated sodium channels by stabilizing their inactive state. Carbamazepin and Phenytoin also act by blocking sodium channels in a voltage-dependent manner. Therefore, all of these drugs are effective in preventing seizures by modulating sodium channel function. The other choices (A, B, C) are incorrect because they individually target sodium channels through voltage-dependent inactivation, distinguishing them from other antiseizure drugs that act through different mechanisms.

Question 4 of 5

Indicate the drug that induces parkinsonian syndromes:

Correct Answer: A

Rationale: Certainly! Chlorpromazine is the correct answer as it is a typical antipsychotic known to induce parkinsonian syndromes as a side effect due to its dopamine-blocking properties. This leads to a decrease in dopamine levels and imbalance in the basal ganglia function, resulting in symptoms resembling Parkinson's disease. Diazepam, Triazolam, and Carbamazepine do not typically induce parkinsonian syndromes as they do not directly affect dopamine levels or basal ganglia function.

Question 5 of 5

Which of the following opioid analgesics can produce an increase in the pulmonary arterial pressure and myocardial work?

Correct Answer: B

Rationale: The correct answer is B: Pentazocine. Pentazocine is a mixed opioid agonist-antagonist that can increase pulmonary arterial pressure and myocardial work due to its kappa agonist activity. Morphine (A) primarily acts on mu-opioid receptors and does not significantly affect pulmonary arterial pressure. Meperidine (C) can cause hypotension rather than an increase in pulmonary arterial pressure. Methadone (D) is a synthetic opioid that has a long duration of action but does not typically cause a significant increase in pulmonary arterial pressure or myocardial work.

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