Indications of severe exacerbation of asthma include the following EXCEPT

Correct Answer: D

Rationale: Severe asthma exacerbations are characterized by symptoms like breathlessness, use of accessory muscles, and mental status changes. A PEF or FEV1 <70% does not necessarily indicate a severe exacerbation.

Correct Answer: D

Rationale: Reye's syndrome is a rare but serious condition that primarily affects children and teenagers. It is characterized by swelling in the liver and the brain. The development of Reye's syndrome has been linked with the use of aspirin during viral infections, particularly influenza and varicella (chickenpox). Therefore, the correct answer is D. Varicella. It is crucial to avoid giving aspirin to children and teenagers during these viral infections to reduce the risk of developing Reye's syndrome.

Correct Answer: C

Rationale: Immunotherapy is not effective for anaphylaxis to a wasp sting, as it is an acute, life-threatening reaction requiring immediate epinephrine.

Correct Answer: B

Rationale: High leukocyte count (>50,000) at diagnosis indicates aggressive disease and poor prognosis. Other poor prognostic factors include CNS involvement and very young or old age at diagnosis.

Correct Answer: C

Rationale: Epstein-Barr virus is less commonly associated with postinfectious arthritis.