ATI RN
Clinical Pharmacology of Cardiovascular Drugs PPT Questions
Question 1 of 5
Indicate the route of local anesthetic administration, which is associated with instillation within epidural or subarachnoid spaces:
Correct Answer: D
Rationale: The correct answer is D: Spinal anesthesia. Spinal anesthesia involves injecting local anesthetics directly into the subarachnoid space, which is within the spinal canal. This allows for the anesthetic to block sensation in the lower part of the body. Topical anesthesia (A) is applied to the surface of the skin, infiltrative anesthesia (B) involves injecting local anesthetics into tissues surrounding the surgical site, and regional anesthesia (C) includes nerve blocks to numb specific areas. Spinal anesthesia is distinct as it targets the spinal nerves directly within the epidural or subarachnoid spaces.
Question 2 of 5
Indicate the nondepolarizing agent, which has short duration of action:
Correct Answer: C
Rationale: Rationale: Mivacurium is the correct answer as it is a nondepolarizing neuromuscular blocking agent with a short duration of action due to its rapid metabolism by plasma esterases. Succinylcholine (A) is a depolarizing agent, Tubocurarine (B) and Pancuronium (D) are nondepolarizing agents with longer durations of action compared to Mivacurium.
Question 3 of 5
Which of the following direct-acting drugs is a relatively pure alfa agonist, an effective mydriatic and decongestant and can be used to raise blood pressure?
Correct Answer: C
Rationale: Rationale: 1. Phenylephrine is a relatively pure alpha agonist, constricts blood vessels, and increases blood pressure. 2. It is an effective mydriatic due to its alpha-adrenergic effects. 3. Phenylephrine is a decongestant by constricting nasal blood vessels. 4. Epinephrine and norepinephrine are non-selective agonists with more diverse effects. 5. Ephedrine acts on both alpha and beta receptors, making it less specific for raising blood pressure.
Question 4 of 5
Characteristics of beta-blocking agents include all of the following EXCEPT:
Correct Answer: C
Rationale: The correct answer is C because beta-blocking agents do not induce depression or deplete stores of catecholamines. Here's the rationale: 1. Option A is correct as beta blockers occupy beta receptors, competitively reducing receptor occupancy by catecholamines. 2. Option B is incorrect because beta blockers can cause hypotension as one of their side effects, especially in individuals with normal blood pressure. 3. Option D is correct as beta blockers can cause blockade in the atrioventricular node, leading to decreased heart rate and conduction. In summary, beta blockers do not induce depression or deplete catecholamine stores, making option C the correct answer.
Question 5 of 5
Indicate the main claim for an ideal hypnotic agent:
Correct Answer: D
Rationale: The correct answer is D because an ideal hypnotic agent should have all the qualities listed in choices A, B, and C. Rapid onset and sufficient duration of action ensure quick and long-lasting sleep induction. Minor effects on sleep patterns indicate minimal disruption to natural sleep cycles. Minimal "hangover" effects mean fewer side effects upon waking up, promoting overall well-being. Therefore, having all these qualities makes a hypnotic agent ideal for promoting healthy and restful sleep.